Melanin-concentrating hormone receptor 1 · SINGLE PROTEIN · Rattus norvegicus
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As of 2026-09-14Protein identity stays anchored to UniProt P97639. Use UniProt P97639 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P97639 as the stable identity anchor, then attach disease evidence before program review.
Melanin-concentrating hormone receptor 1
Review this target as Melanin-concentrating hormone receptor 1, mapped to UniProt P97639. Sequence length is 353 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Melanin-concentrating hormone receptor 1 as ChEMBL target CHEMBL1075228, mapped to UniProt P97639. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Melanin-concentrating hormone receptor 1 |
| Target Type | SINGLE PROTEIN |
| Organism | Rattus norvegicus |
| UniProt | P97639 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Melanin-concentrating hormone receptor 1 |
| UniProt Accession | P97639 |
| Component Type | Protein |
| Sequence Length | 353 aa |
Melanin-concentrating hormone receptor 1
Review this target as Melanin-concentrating hormone receptor 1, mapped to UniProt P97639. Sequence length is 353 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL185271 | 9.6 | Ki | 0.25 | Preclinical |
| CHEMBL3618330 | 9.52 | Ki | 0.3 | Preclinical |
| CHEMBL214957 | 9.47 | Ki | 0.34 | Preclinical |
| CHEMBL3618324 | 9.4 | Ki | 0.4 | Preclinical |
| CHEMBL3618325 | 9.3 | Ki | 0.5 | Preclinical |
| CHEMBL5613278 | 9.28 | Ki | 0.52 | Preclinical |
| CHEMBL5611933 | 9.26 | Ki | 0.55 | Preclinical |
| CHEMBL388440 | 9.22 | Ki | 0.6 | Preclinical |
| CHEMBL429464 | 9.21 | Ki | 0.62 | Preclinical |
| CHEMBL5612007 | 9.21 | Ki | 0.62 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 16 | 88 | 7.8 |
| cell-based format | 10 | 180 | 7.8 |
| cell membrane format | 1 | 24 | 9.0 |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 8 | 66 | 6.8 |