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Target Snapshot

CHEMBL1075362 Target Snapshot

Trypanosoma evansi · ORGANISM · Trypanosoma evansi

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120Compounds
21Assays
1Approved Drugs
74.0Activities
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Broader Open DB context

Frame the target before identity details

Structured disease, protein, and project context should read before the lower-level identity rail.

As of 2026-09-13

Confirm a stable target identifier before relying on this context across project surfaces.

Review focus
Open DB context pending

Confirm a stable target identifier before relying on this context across project surfaces.

ChEMBL component mapping + Open Targets-ready proxy + ChEMBL 36 via Core Engine 2026-09-13
Open source guide
Identity Layer

Cross-source identity

Keep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.

This review treats Trypanosoma evansi as ChEMBL target CHEMBL1075362. Disease framing currently uses the Open Targets-ready proxy contract.

Review anchor
Trypanosoma evansi
ORGANISM · Trypanosoma evansi
As of 2026-09-13
ChEMBL target ID
CHEMBL1075362
Primary anchor for compounds, assays, approvals, and exports
ChEMBL 36 via Core Engine As of 2026-09-13
www.ebi.ac.uk
Disease evidence contract
Open Targets-ready proxy
ChEMBL drug mechanism + indication proxy
ChEMBL drug mechanism + indication proxy As of 2026-09-13
www.ebi.ac.uk

Reuse the same identifiers in notes, watch rules, exports, and review packs so provenance stays stable across surfaces.

Source Guidance

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Need stable target naming and protein identity?
UniProt Target Context
UniProt accession via ChEMBL component mapping

Start here when your first question is whether Trypanosoma evansi still has a stable protein naming contract across sources.

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Need disease fit before discussing compounds?
Disease Relevance & Evidence Level
ChEMBL drug mechanism + indication proxy

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Evidence Card
Review-ready rationale with source-aware context

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Overview

Basic Information

Verify identity, organism, and the fastest next research jumps from the same page.

Preferred NameTrypanosoma evansi
Target TypeORGANISM
OrganismTrypanosoma evansi
ChEMBL ↗ NCBI Taxonomy ↗

Next Actions

SearchRun a focused querySearch the database using this target name as the starting context. ApprovalsCheck approved moleculesSee which approved drugs connect back to this target and its surrounding signal space. FeedScan papers & updatesStay in the project thread while checking recent papers and platform updates.
UniProt Context

UniProt Target Context

Reviewable protein naming and mapping context for this target snapshot.

Protein LabelTrypanosoma evansi
UniProt AccessionN/A

Trypanosoma evansi

Source · UniProt accession via ChEMBL component mapping
UniProt Context ↗
Review Cue

How to read this target

Review this target as Trypanosoma evansi.

Review nameTrypanosoma evansi
OrganismTrypanosoma evansi
Clinical Profile

Clinical Phase Distribution

1
Approved
2
Phase III
1
Phase II
Assay Mix

Activity Type Distribution

IC5064.0
EC5010.0
Lead Set

Top Inhibitors (by pChEMBL)

ChEMBL IDpChEMBLTypeValue (nM)Phase
CHEMBL35241 7.75 EC50 18.0 Clinical
CHEMBL1086746 6.77 EC50 170.0 Preclinical
CHEMBL1088447 6.68 EC50 210.0 Preclinical
CHEMBL265502 6.42 IC50 380.0 Clinical
CHEMBL4855819 6.38 IC50 420.0 Preclinical
CHEMBL4878845 6.09 IC50 810.0 Preclinical
CHEMBL103410 5.96 EC50 1100.0 Preclinical
CHEMBL1082223 5.82 EC50 1500.0 Preclinical
CHEMBL1087679 5.8 EC50 1600.0 Preclinical
CHEMBL140 5.7 EC50 2000.0 Clinical
Distribution

pChEMBL Value Distribution

5
5.0
8
5.5
3
6.0
2
6.5
0
7.0
1
7.5
0
8.0
0
8.5
0
9.0
0
9.5
pChEMBL
Assay Landscape

Assay Landscape

22
Total Assays
48
Tested Compounds
1
Assay Types
Functional — 22 assays, 48 compounds
BAO Format Assays Compounds Avg pChEMBL
organism-based format 22 48 5.0

Confidence Score Distribution

Source · ChEMBL 36 via Core Engine