Transient receptor potential cation channel subfamily M member 2 · SINGLE PROTEIN · Homo sapiens
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As of 2026-09-14Protein identity stays anchored to UniProt O94759. Use UniProt O94759 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt O94759 as the stable identity anchor, then attach disease evidence before program review.
Transient receptor potential cation channel subfamily M member 2
Review this target as Transient receptor potential cation channel subfamily M member 2, mapped to UniProt O94759. Sequence length is 1503 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Transient receptor potential cation channel subfamily M member 2 as ChEMBL target CHEMBL1250402, mapped to UniProt O94759. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Transient receptor potential cation channel subfamily M member 2 |
| Target Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
| UniProt | O94759 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Transient receptor potential cation channel subfamily M member 2 |
| UniProt Accession | O94759 |
| Component Type | Protein |
| Sequence Length | 1503 aa |
Transient receptor potential cation channel subfamily M member 2
Review this target as Transient receptor potential cation channel subfamily M member 2, mapped to UniProt O94759. Sequence length is 1503 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL4878260 | 7.89 | IC50 | 13.0 | Preclinical |
| CHEMBL4161122 | 7.6 | IC50 | 25.0 | Preclinical |
| CHEMBL487005 | 6.68 | IC50 | 210.0 | Preclinical |
| CHEMBL173443 | 6.5 | IC50 | 320.0 | Preclinical |
| CHEMBL4863360 | 6.4 | IC50 | 398.0 | Preclinical |
| CHEMBL4864346 | 6.39 | IC50 | 410.0 | Preclinical |
| CHEMBL4856222 | 6.33 | IC50 | 467.0 | Preclinical |
| CHEMBL127336 | 6.22 | IC50 | 600.0 | Preclinical |
| CHEMBL4863549 | 6.1 | IC50 | 788.0 | Preclinical |
| CHEMBL4849043 | 6.08 | IC50 | 830.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 43 | 32 | 5.5 |
| single protein format | 8 | 5 | 4.1 |
| assay format | 1 | 1 | 4.2 |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 1 | 0 | — |