Lysosomal Pro-X carboxypeptidase · SINGLE PROTEIN · Mus musculus
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As of 2026-09-14Protein identity stays anchored to UniProt Q7TMR0. Use UniProt Q7TMR0 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt Q7TMR0 as the stable identity anchor, then attach disease evidence before program review.
Lysosomal Pro-X carboxypeptidase
Review this target as Lysosomal Pro-X carboxypeptidase, mapped to UniProt Q7TMR0. Sequence length is 491 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Lysosomal Pro-X carboxypeptidase as ChEMBL target CHEMBL1255149, mapped to UniProt Q7TMR0. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Lysosomal Pro-X carboxypeptidase |
| Target Type | SINGLE PROTEIN |
| Organism | Mus musculus |
| UniProt | Q7TMR0 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Lysosomal Pro-X carboxypeptidase |
| UniProt Accession | Q7TMR0 |
| Component Type | Protein |
| Sequence Length | 491 aa |
Lysosomal Pro-X carboxypeptidase
Review this target as Lysosomal Pro-X carboxypeptidase, mapped to UniProt Q7TMR0. Sequence length is 491 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL1950444 | 10.41 | IC50 | 0.039 | Preclinical |
| CHEMBL1951478 | 9.96 | IC50 | 0.11 | Preclinical |
| CHEMBL1951465 | 9.74 | IC50 | 0.18 | Preclinical |
| CHEMBL2031595 | 9.7 | IC50 | 0.2 | Preclinical |
| CHEMBL3086040 | 9.55 | IC50 | 0.28 | Preclinical |
| CHEMBL2023210 | 9.52 | IC50 | 0.3 | Preclinical |
| CHEMBL1951474 | 9.51 | IC50 | 0.31 | Preclinical |
| CHEMBL1951468 | 9.42 | IC50 | 0.38 | Preclinical |
| CHEMBL1951476 | 9.41 | IC50 | 0.39 | Preclinical |
| CHEMBL1938510 | 9.4 | IC50 | 0.4 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 15 | 155 | 7.8 |
| organism-based format | 6 | 0 | — |
| cell-based format | 1 | 0 | — |
| cell-free format | 1 | 16 | 6.7 |