Use UniProt C4YTQ8 as the stable identity anchor, then attach disease evidence before program review.
CHEMBL1293251 Target Snapshot
ATP-dependent molecular chaperone HSP82 · SINGLE PROTEIN · Candida albicans (strain WO-1) (Yeast)
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As of 2026-09-13Protein identity stays anchored to UniProt C4YTQ8. Use UniProt C4YTQ8 as the stable identity anchor, then attach disease evidence before program review.
ATP-dependent molecular chaperone HSP82
Review this target as ATP-dependent molecular chaperone HSP82, mapped to UniProt C4YTQ8. Sequence length is 707 aa.
Protein source · UniProt accession via ChEMBL component mappingCross-source identity
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This review treats ATP-dependent molecular chaperone HSP82 as ChEMBL target CHEMBL1293251, mapped to UniProt C4YTQ8. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | ATP-dependent molecular chaperone HSP82 |
| Target Type | SINGLE PROTEIN |
| Organism | Candida albicans (strain WO-1) (Yeast) |
| UniProt | C4YTQ8 |
Next Actions
UniProt Target Context
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | ATP-dependent molecular chaperone HSP82 |
| UniProt Accession | C4YTQ8 |
| Component Type | Protein |
| Sequence Length | 707 aa |
ATP-dependent molecular chaperone HSP82
How to read this target
Review this target as ATP-dependent molecular chaperone HSP82, mapped to UniProt C4YTQ8. Sequence length is 707 aa.
Clinical Phase Distribution
Activity Type Distribution
Top Inhibitors (by pChEMBL)
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL104 | 6.88 | EC50 | 133.0 | Approved |
| CHEMBL518252 | 6.88 | EC50 | 132.0 | Preclinical |
| CHEMBL1524829 | 6.88 | EC50 | 131.0 | Preclinical |
| CHEMBL2005246 | 6.88 | EC50 | 133.0 | Preclinical |
| CHEMBL1352792 | 6.87 | EC50 | 135.0 | Preclinical |
| CHEMBL1431710 | 6.87 | EC50 | 134.0 | Preclinical |
| CHEMBL3392051 | 6.87 | EC50 | 135.0 | Preclinical |
| CHEMBL1408094 | 6.84 | EC50 | 146.0 | Preclinical |
| CHEMBL1521297 | 6.84 | EC50 | 146.0 | Preclinical |
| CHEMBL585502 | 6.83 | EC50 | 149.0 | Preclinical |
pChEMBL Value Distribution
Approved Drugs
Assay Landscape
Functional — 3 assays, 1,140 compounds
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 3 | 1,140 | 5.5 |