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Target Snapshot

CHEMBL1293251 Target Snapshot

ATP-dependent molecular chaperone HSP82 · SINGLE PROTEIN · Candida albicans (strain WO-1) (Yeast)

1,499Compounds
3Assays
7Approved Drugs
2,186.0Activities
Free Research Context

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Broader Open DB context

Frame the target before identity details

Structured disease, protein, and project context should read before the lower-level identity rail.

As of 2026-09-13

Protein identity stays anchored to UniProt C4YTQ8. Use UniProt C4YTQ8 as the stable identity anchor, then attach disease evidence before program review.

Review focus
Protein anchor ready

Use UniProt C4YTQ8 as the stable identity anchor, then attach disease evidence before program review.

ChEMBL component mapping + Open Targets-ready proxy + ChEMBL 36 via Core Engine 2026-09-13
Open source guide
Identity Layer

Cross-source identity

Keep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.

This review treats ATP-dependent molecular chaperone HSP82 as ChEMBL target CHEMBL1293251, mapped to UniProt C4YTQ8. Disease framing currently uses the Open Targets-ready proxy contract.

Review anchor
ATP-dependent molecular chaperone HSP82
SINGLE PROTEIN · Candida albicans (strain WO-1) (Yeast)
As of 2026-09-13
ChEMBL target ID
CHEMBL1293251
Primary anchor for compounds, assays, approvals, and exports
ChEMBL 36 via Core Engine As of 2026-09-13
www.ebi.ac.uk
UniProt accession
C4YTQ8
ATP-dependent molecular chaperone HSP82
UniProt accession via ChEMBL component mapping As of 2026-09-13
www.uniprot.org
Disease evidence contract
Open Targets-ready proxy
ChEMBL drug mechanism + indication proxy
ChEMBL drug mechanism + indication proxy As of 2026-09-13
www.ebi.ac.uk

Reuse the same identifiers in notes, watch rules, exports, and review packs so provenance stays stable across surfaces.

Source Guidance

Start with the right source

Choose the first block or source based on the question you are trying to answer.

Need stable target naming and protein identity?
UniProt Target Context
UniProt accession via ChEMBL component mapping

Start here when your first question is whether ATP-dependent molecular chaperone HSP82 is the right protein anchor across sources, using UniProt C4YTQ8 as the stable mapping.

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Disease Relevance & Evidence Level
ChEMBL drug mechanism + indication proxy

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Evidence Card
Review-ready rationale with source-aware context

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Overview

Basic Information

Verify identity, organism, and the fastest next research jumps from the same page.

UniProt Context

UniProt Target Context

Reviewable protein naming and mapping context for this target snapshot.

Protein LabelATP-dependent molecular chaperone HSP82
UniProt AccessionC4YTQ8
Component TypeProtein
Sequence Length707 aa

ATP-dependent molecular chaperone HSP82

Source · UniProt accession via ChEMBL component mapping
Review Cue

How to read this target

Review this target as ATP-dependent molecular chaperone HSP82, mapped to UniProt C4YTQ8. Sequence length is 707 aa.

Mapped IDC4YTQ8
Review nameATP-dependent molecular chaperone HSP82
OrganismCandida albicans (strain WO-1) (Yeast)
Clinical Profile

Clinical Phase Distribution

7
Approved
1
Phase I
Assay Mix

Activity Type Distribution

EC502,186.0
Lead Set

Top Inhibitors (by pChEMBL)

ChEMBL IDpChEMBLTypeValue (nM)Phase
CHEMBL104 6.88 EC50 133.0 Approved
CHEMBL518252 6.88 EC50 132.0 Preclinical
CHEMBL1524829 6.88 EC50 131.0 Preclinical
CHEMBL2005246 6.88 EC50 133.0 Preclinical
CHEMBL1352792 6.87 EC50 135.0 Preclinical
CHEMBL1431710 6.87 EC50 134.0 Preclinical
CHEMBL3392051 6.87 EC50 135.0 Preclinical
CHEMBL1408094 6.84 EC50 146.0 Preclinical
CHEMBL1521297 6.84 EC50 146.0 Preclinical
CHEMBL585502 6.83 EC50 149.0 Preclinical
Distribution

pChEMBL Value Distribution

286
5.0
437
5.5
301
6.0
50
6.5
0
7.0
0
7.5
0
8.0
0
8.5
0
9.0
0
9.5
pChEMBL
Approved Drugs

Approved Drugs

CLOTRIMAZOLE
CHEMBL104
Approved 1975
FLUCYTOSINE
CHEMBL1463
Approved 1971
DEFEROXAMINE MESYLATE
CHEMBL1234
Approved 1968
Assay Landscape

Assay Landscape

3
Total Assays
1,140
Tested Compounds
1
Assay Types
Functional — 3 assays, 1,140 compounds
BAO Format Assays Compounds Avg pChEMBL
cell-based format 3 1,140 5.5

Confidence Score Distribution

Source · ChEMBL 36 via Core Engine