Nuclear receptor coactivator 1 · SINGLE PROTEIN · Homo sapiens
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As of 2026-09-14Protein identity stays anchored to UniProt Q15788. Use UniProt Q15788 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt Q15788 as the stable identity anchor, then attach disease evidence before program review.
Nuclear receptor coactivator 1
Review this target as Nuclear receptor coactivator 1, mapped to UniProt Q15788. Sequence length is 1441 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Nuclear receptor coactivator 1 as ChEMBL target CHEMBL1615387, mapped to UniProt Q15788. Disease framing currently uses the Open Targets-ready proxy contract.
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Start here when your first question is whether Nuclear receptor coactivator 1 is the right protein anchor across sources, using UniProt Q15788 as the stable mapping.
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| Preferred Name | Nuclear receptor coactivator 1 |
| Target Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
| UniProt | Q15788 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Nuclear receptor coactivator 1 |
| UniProt Accession | Q15788 |
| Component Type | Protein |
| Sequence Length | 1441 aa |
Nuclear receptor coactivator 1
Review this target as Nuclear receptor coactivator 1, mapped to UniProt Q15788. Sequence length is 1441 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL1808264 | 8.0 | IC50 | 10.0 | Preclinical |
| CHEMBL44657 | 5.94 | IC50 | 1153.0 | Approved |
| CHEMBL1610875 | 5.61 | IC50 | 2442.0 | Preclinical |
| CHEMBL1418980 | 5.55 | IC50 | 2843.0 | Preclinical |
| CHEMBL1469670 | 5.47 | IC50 | 3371.0 | Preclinical |
| CHEMBL1705854 | 5.46 | IC50 | 3449.0 | Preclinical |
| CHEMBL2373711 | 5.43 | IC50 | 3715.0 | Preclinical |
| CHEMBL1564670 | 5.41 | IC50 | 3871.0 | Preclinical |
| CHEMBL1528507 | 5.4 | IC50 | 3973.0 | Preclinical |
| CHEMBL1307972 | 5.37 | IC50 | 4256.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 1 | 1 | 8.0 |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 1 | 155 | 4.9 |