Compound Detail
CHEMBL1469670
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Basic Information
| ChEMBL ID | CHEMBL1469670 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | GGSCOGVZVMPTFS-LGMDPLHJSA-N |
4
Targets
5
Activities
1
Assay Types
0
PK Parameters
0
Publications
0
Known Names
Molecular Properties
388.6
MW (Da)
4.04
ALogP
4
HBA
1
HBD
49.4
PSA (Ų)
0.59
QED
0
Ro5 Violations
6
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 5 meas. best 6.14
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Unchecked CHEMBL612545 | IC50 | 6.14 | 6.045 | 730.0 | 2 |
| Nuclear receptor coactivator 3 CHEMBL1615382 | IC50 | 5.8 | 5.8 | 1583.0 | 1 |
| Nuclear receptor coactivator 1 CHEMBL1615387 | IC50 | 5.47 | 5.47 | 3371.0 | 1 |
| Tegument protein VP16 CHEMBL4218 | IC50 | 5.27 | 5.27 | 5373.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Unchecked | IC50 | = | 730.0 | nM | 6.14 | PUBCHEM_BIOASSAY: Dose Response selectivity of uHTS chemical inhibitors of B-cel... | - |
| Unchecked | IC50 | = | 1130.0 | nM | 5.95 | PUBCHEM_BIOASSAY: Dose response confirmation of uHTS of chemical inhibitors of B... | - |
| Nuclear receptor coactivator 3 | IC50 | = | 1583.0 | nM | 5.8 | PUBCHEM_BIOASSAY: Counterscreen for inhibitors of the Steroid Receptor Coactivat... | - |
| Nuclear receptor coactivator 1 | IC50 | = | 3371.0 | nM | 5.47 | PUBCHEM_BIOASSAY: Luminescence-based cell-based high throughput dose response as... | - |
| Tegument protein VP16 | IC50 | = | 5373.0 | nM | 5.27 | PUBCHEM_BIOASSAY: Counterscreen for inhibitors of the Steroid Receptor Coactivat... | - |
Data from ChEMBL 36 via Core Engine