Neuraminidase · SINGLE PROTEIN · Influenza A virus
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As of 2026-09-14Protein identity stays anchored to UniProt C4LRQ6. Use UniProt C4LRQ6 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt C4LRQ6 as the stable identity anchor, then attach disease evidence before program review.
Neuraminidase
Review this target as Neuraminidase, mapped to UniProt C4LRQ6. Sequence length is 449 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Neuraminidase as ChEMBL target CHEMBL1667686, mapped to UniProt C4LRQ6. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Neuraminidase |
| Target Type | SINGLE PROTEIN |
| Organism | Influenza A virus |
| UniProt | C4LRQ6 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Neuraminidase |
| UniProt Accession | C4LRQ6 |
| Component Type | Protein |
| Sequence Length | 449 aa |
Neuraminidase
Review this target as Neuraminidase, mapped to UniProt C4LRQ6. Sequence length is 449 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL1229 | 10.0 | IC50 | 0.1 | Approved |
| CHEMBL222813 | 9.3 | Ki | 0.5 | Approved |
| CHEMBL222813 | 9.22 | IC50 | 0.6 | Approved |
| CHEMBL1229 | 8.96 | Ki | 1.1 | Approved |
| CHEMBL139367 | 6.84 | IC50 | 146.0 | Approved |
| CHEMBL3342485 | 6.8 | IC50 | 160.0 | Preclinical |
| CHEMBL4161935 | 6.41 | IC50 | 387.07 | Preclinical |
| CHEMBL4288995 | 6.37 | IC50 | 426.0 | Preclinical |
| CHEMBL4288789 | 6.25 | IC50 | 564.0 | Preclinical |
| CHEMBL4175983 | 6.18 | IC50 | 663.9 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 6 | 15 | 6.7 |
| cell-based format | 2 | 3 | 6.4 |