Use UniProt P53624 as the stable identity anchor, then attach disease evidence before program review.
CHEMBL1697673 Target Snapshot
Mannosyl-oligosaccharide alpha-1,2-mannosidase isoform B · SINGLE PROTEIN · Drosophila melanogaster
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As of 2026-09-14Protein identity stays anchored to UniProt P53624. Use UniProt P53624 as the stable identity anchor, then attach disease evidence before program review.
Mannosyl-oligosaccharide alpha-1,2-mannosidase IA
Review this target as Mannosyl-oligosaccharide alpha-1,2-mannosidase isoform B, mapped to UniProt P53624. ChEMBL maps the protein component as Mannosyl-oligosaccharide alpha-1,2-mannosidase IA. Sequence length is 667 aa.
Protein source · UniProt accession via ChEMBL component mappingCross-source identity
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This review treats Mannosyl-oligosaccharide alpha-1,2-mannosidase isoform B as ChEMBL target CHEMBL1697673, mapped to UniProt P53624. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Mannosyl-oligosaccharide alpha-1,2-mannosidase isoform B |
| Target Type | SINGLE PROTEIN |
| Organism | Drosophila melanogaster |
| UniProt | P53624 |
Next Actions
UniProt Target Context
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Mannosyl-oligosaccharide alpha-1,2-mannosidase IA |
| UniProt Accession | P53624 |
| Component Type | Protein |
| Sequence Length | 667 aa |
Mannosyl-oligosaccharide alpha-1,2-mannosidase IA
How to read this target
Review this target as Mannosyl-oligosaccharide alpha-1,2-mannosidase isoform B, mapped to UniProt P53624. ChEMBL maps the protein component as Mannosyl-oligosaccharide alpha-1,2-mannosidase IA. Sequence length is 667 aa.
Clinical Phase Distribution
Activity Type Distribution
Top Inhibitors (by pChEMBL)
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL371197 | 8.52 | Ki | 3.0 | Clinical |
| CHEMBL371197 | 8.3 | IC50 | 5.0 | Clinical |
| CHEMBL9623 | 6.82 | IC50 | 150.0 | Preclinical |
pChEMBL Value Distribution
Assay Landscape
Binding — 2 assays, 7 compounds
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 2 | 7 | 7.9 |