X-box-binding protein 1 · SINGLE PROTEIN · Homo sapiens
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Structured disease, protein, and project context should read before the lower-level identity rail.
As of 2026-09-14Protein identity stays anchored to UniProt P17861. Use UniProt P17861 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P17861 as the stable identity anchor, then attach disease evidence before program review.
X-box-binding protein 1
Review this target as X-box-binding protein 1, mapped to UniProt P17861. Sequence length is 261 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats X-box-binding protein 1 as ChEMBL target CHEMBL1741176, mapped to UniProt P17861. Disease framing currently uses the Open Targets-ready proxy contract.
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Start here when your first question is whether X-box-binding protein 1 is the right protein anchor across sources, using UniProt P17861 as the stable mapping.
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| Preferred Name | X-box-binding protein 1 |
| Target Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
| UniProt | P17861 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | X-box-binding protein 1 |
| UniProt Accession | P17861 |
| Component Type | Protein |
| Sequence Length | 261 aa |
X-box-binding protein 1
Review this target as X-box-binding protein 1, mapped to UniProt P17861. Sequence length is 261 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL3331117 | 8.65 | EC50 | 2.25 | Preclinical |
| CHEMBL1312928 | 6.8 | IC50 | 160.0 | Preclinical |
| CHEMBL1329798 | 6.8 | IC50 | 160.0 | Preclinical |
| CHEMBL1405952 | 6.8 | IC50 | 160.0 | Preclinical |
| CHEMBL1409900 | 6.8 | IC50 | 160.0 | Preclinical |
| CHEMBL1452159 | 6.8 | IC50 | 160.0 | Preclinical |
| CHEMBL1453996 | 6.8 | IC50 | 160.0 | Preclinical |
| CHEMBL1507250 | 6.8 | IC50 | 160.0 | Preclinical |
| CHEMBL1518905 | 6.8 | IC50 | 160.0 | Preclinical |
| CHEMBL1521960 | 6.8 | IC50 | 160.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 6 | 4 | 6.5 |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| assay format | 1 | 580 | 5.3 |