General amino acid permease AGP1 · SINGLE PROTEIN · Saccharomyces cerevisiae S288c
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Structured disease, protein, and project context should read before the lower-level identity rail.
As of 2026-09-14Protein identity stays anchored to UniProt P25376. Use UniProt P25376 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P25376 as the stable identity anchor, then attach disease evidence before program review.
General amino acid permease AGP1
Review this target as General amino acid permease AGP1, mapped to UniProt P25376. Sequence length is 633 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats General amino acid permease AGP1 as ChEMBL target CHEMBL1741178, mapped to UniProt P25376. Disease framing currently uses the Open Targets-ready proxy contract.
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Start here when your first question is whether General amino acid permease AGP1 is the right protein anchor across sources, using UniProt P25376 as the stable mapping.
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| Preferred Name | General amino acid permease AGP1 |
| Target Type | SINGLE PROTEIN |
| Organism | Saccharomyces cerevisiae S288c |
| UniProt | P25376 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | General amino acid permease AGP1 |
| UniProt Accession | P25376 |
| Component Type | Protein |
| Sequence Length | 633 aa |
General amino acid permease AGP1
Review this target as General amino acid permease AGP1, mapped to UniProt P25376. Sequence length is 633 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL1417204 | 6.52 | EC50 | 305.0 | Preclinical |
| CHEMBL1425137 | 6.24 | EC50 | 570.0 | Preclinical |
| CHEMBL1492648 | 6.18 | EC50 | 653.0 | Preclinical |
| CHEMBL1584597 | 6.11 | EC50 | 781.0 | Preclinical |
| CHEMBL3199814 | 6.08 | EC50 | 822.0 | Preclinical |
| CHEMBL1430895 | 6.06 | EC50 | 872.0 | Preclinical |
| CHEMBL1370681 | 6.03 | EC50 | 943.0 | Preclinical |
| CHEMBL1429929 | 6.03 | EC50 | 941.0 | Preclinical |
| CHEMBL1449204 | 5.86 | EC50 | 1379.0 | Preclinical |
| CHEMBL1522211 | 5.71 | EC50 | 1939.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| assay format | 2 | 19 | 5.7 |