Compound Detail
CHEMBL1425137
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Basic Information
| ChEMBL ID | CHEMBL1425137 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | XJFGZQMRELIYGR-UHFFFAOYSA-N |
3
Targets
3
Activities
2
Assay Types
0
PK Parameters
0
Publications
0
Known Names
Molecular Properties
253.7
MW (Da)
2.85
ALogP
2
HBA
1
HBD
46.2
PSA (Ų)
0.67
QED
0
Ro5 Violations
3
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
EC50 2 meas. best 6.24
IC50 1 meas. best 6.16
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| General amino acid permease AGP1 CHEMBL1741178 | EC50 | 6.24 | 6.24 | 570.0 | 1 |
| G-protein coupled receptor 55 CHEMBL1075322 | IC50 | 6.16 | 6.16 | 696.1 | 1 |
| Large ribosomal subunit protein eL19A CHEMBL1741172 | EC50 | 4.95 | 4.95 | 11200.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| General amino acid permease AGP1 | EC50 | = | 570.0 | nM | 6.24 | PUBCHEM_BIOASSAY: Dose Response of TOR pathway GFP-fusion proteins in Saccharomy... | - |
| G-protein coupled receptor 55 | IC50 | = | 696.1 | nM | 6.16 | PUBCHEM_BIOASSAY: Image-Based HTS for Selective Antagonists for GPR55. (Class of... | - |
| Large ribosomal subunit protein eL19A | EC50 | = | 11200.0 | nM | 4.95 | PUBCHEM_BIOASSAY: Dose Response of TOR pathway GFP-fusion proteins in Saccharomy... | - |
Data from ChEMBL 36 via Core Engine