Use UniProt Q8IL32 as the stable identity anchor, then attach disease evidence before program review.
CHEMBL1795086 Target Snapshot
HSP90 · SINGLE PROTEIN · Plasmodium falciparum 3D7
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As of 2026-09-14Protein identity stays anchored to UniProt Q8IL32. Use UniProt Q8IL32 as the stable identity anchor, then attach disease evidence before program review.
Heat shock protein 90, putative
Review this target as HSP90, mapped to UniProt Q8IL32. ChEMBL maps the protein component as Heat shock protein 90, putative. Sequence length is 927 aa.
Protein source · UniProt accession via ChEMBL component mappingCross-source identity
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This review treats HSP90 as ChEMBL target CHEMBL1795086, mapped to UniProt Q8IL32. Disease framing currently uses the Open Targets-ready proxy contract.
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Open Review-ready CardBasic Information
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| Preferred Name | HSP90 |
| Target Type | SINGLE PROTEIN |
| Organism | Plasmodium falciparum 3D7 |
| UniProt | Q8IL32 |
Next Actions
UniProt Target Context
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Heat shock protein 90, putative |
| UniProt Accession | Q8IL32 |
| Component Type | Protein |
| Sequence Length | 927 aa |
Heat shock protein 90, putative
How to read this target
Review this target as HSP90, mapped to UniProt Q8IL32. ChEMBL maps the protein component as Heat shock protein 90, putative. Sequence length is 927 aa.
Clinical Phase Distribution
Activity Type Distribution
Top Inhibitors (by pChEMBL)
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL598685 | 8.15 | Kd | 7.0 | Preclinical |
| CHEMBL585793 | 7.57 | Kd | 27.0 | Preclinical |
| CHEMBL278315 | 6.77 | Kd | 169.0 | Clinical |
| CHEMBL4803806 | 4.91 | IC50 | 12200.0 | Preclinical |
| CHEMBL3234416 | 4.85 | Kd | 14100.0 | Preclinical |
| CHEMBL3234417 | 4.59 | Kd | 25400.0 | Preclinical |
| CHEMBL4446324 | 4.59 | Kd | 25600.0 | Preclinical |
pChEMBL Value Distribution
Assay Landscape
Binding — 6 assays, 10 compounds
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| assay format | 3 | 7 | 5.3 |
| single protein format | 2 | 2 | 7.9 |
| cell-based format | 1 | 1 | 4.9 |
Functional — 1 assays, 0 compounds
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| organism-based format | 1 | 0 | — |