Endoribonuclease toxin MazF · SINGLE PROTEIN · Escherichia coli K-12
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As of 2026-09-14Protein identity stays anchored to UniProt P0AE70. Use UniProt P0AE70 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P0AE70 as the stable identity anchor, then attach disease evidence before program review.
Endoribonuclease toxin MazF
Review this target as Endoribonuclease toxin MazF, mapped to UniProt P0AE70. Sequence length is 111 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Endoribonuclease toxin MazF as ChEMBL target CHEMBL1795096, mapped to UniProt P0AE70. Disease framing currently uses the Open Targets-ready proxy contract.
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Start here when your first question is whether Endoribonuclease toxin MazF is the right protein anchor across sources, using UniProt P0AE70 as the stable mapping.
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| Preferred Name | Endoribonuclease toxin MazF |
| Target Type | SINGLE PROTEIN |
| Organism | Escherichia coli K-12 |
| UniProt | P0AE70 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Endoribonuclease toxin MazF |
| UniProt Accession | P0AE70 |
| Component Type | Protein |
| Sequence Length | 111 aa |
Endoribonuclease toxin MazF
Review this target as Endoribonuclease toxin MazF, mapped to UniProt P0AE70. Sequence length is 111 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL1324227 | 6.57 | EC50 | 271.0 | Preclinical |
| CHEMBL1878187 | 5.94 | EC50 | 1140.0 | Preclinical |
| CHEMBL1583552 | 5.71 | EC50 | 1930.0 | Preclinical |
| CHEMBL1897572 | 5.47 | EC50 | 3350.0 | Preclinical |
| CHEMBL1497357 | 5.46 | EC50 | 3480.0 | Preclinical |
| CHEMBL1723854 | 5.45 | EC50 | 3550.0 | Preclinical |
| CHEMBL1714498 | 5.42 | EC50 | 3830.0 | Preclinical |
| CHEMBL1370456 | 5.4 | EC50 | 3960.0 | Preclinical |
| CHEMBL1325286 | 5.39 | EC50 | 4100.0 | Preclinical |
| CHEMBL1477749 | 5.35 | EC50 | 4480.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| assay format | 4 | 222 | 4.6 |