Chitinase · SINGLE PROTEIN · Onchocerca volvulus
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As of 2026-09-14Protein identity stays anchored to UniProt Q25615. Use UniProt Q25615 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt Q25615 as the stable identity anchor, then attach disease evidence before program review.
Chitinase
Review this target as Chitinase, mapped to UniProt Q25615. Sequence length is 497 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Chitinase as ChEMBL target CHEMBL1795119, mapped to UniProt Q25615. Disease framing currently uses the Open Targets-ready proxy contract.
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Start here when your first question is whether Chitinase is the right protein anchor across sources, using UniProt Q25615 as the stable mapping.
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| Preferred Name | Chitinase |
| Target Type | SINGLE PROTEIN |
| Organism | Onchocerca volvulus |
| UniProt | Q25615 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Chitinase |
| UniProt Accession | Q25615 |
| Component Type | Protein |
| Sequence Length | 497 aa |
Chitinase
Review this target as Chitinase, mapped to UniProt Q25615. Sequence length is 497 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL287542 | 6.89 | Ki | 130.0 | Clinical |
| CHEMBL287542 | 6.47 | IC50 | 340.0 | Clinical |
| CHEMBL3298112 | 6.43 | IC50 | 370.0 | Preclinical |
| CHEMBL3740813 | 6.39 | IC50 | 410.0 | Preclinical |
| CHEMBL3740895 | 6.39 | IC50 | 410.0 | Preclinical |
| CHEMBL12131 | 6.33 | Ki | 468.0 | Clinical |
| CHEMBL3298110 | 6.33 | IC50 | 470.0 | Preclinical |
| CHEMBL3741098 | 6.28 | IC50 | 520.0 | Preclinical |
| CHEMBL3298103 | 6.22 | IC50 | 600.0 | Preclinical |
| CHEMBL1801794 | 6.2 | IC50 | 630.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 5 | 34 | 5.9 |
| tissue-based format | 4 | 8 | 5.4 |