Compound Detail
CHEMBL287542
RAFOXANIDE 🧪 Phase II
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🧪 Phase II
Basic Information
| ChEMBL ID | CHEMBL287542 |
| Name | RAFOXANIDE |
| Phase | Phase II |
| Structure Type | MOL |
| InChI Key | NEMNPWINWMHUMR-UHFFFAOYSA-N |
13
Targets
26
Activities
3
Assay Types
0
PK Parameters
20
Publications
3
Known Names
Molecular Properties
626.0
MW (Da)
6.95
ALogP
3
HBA
2
HBD
58.6
PSA (Ų)
0.31
QED
2
Ro5 Violations
4
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Chirality | Achiral |
Activity Summary
IC50 18 meas. best 8.08
EC50 7 meas. best 7.1
Ki 1 meas. best 6.89
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Unchecked CHEMBL612545 | IC50 | 8.08 | 6.8418 | 8.4 | 11 |
| Streptococcus sp. 'group A' CHEMBL612389 | EC50 | 7.1 | 7.1 | 80.0 | 1 |
| Chitinase CHEMBL1795119 | Ki | 6.89 | 6.89 | 130.0 | 1 |
| Streptococcus CHEMBL612313 | EC50 | 6.86 | 6.86 | 137.0 | 1 |
| Staphylococcus aureus CHEMBL352 | EC50 | 6.5 | 6.485 | 320.0 | 2 |
| Chitinase CHEMBL1795119 | IC50 | 6.47 | 6.47 | 340.0 | 1 |
| Enterococcus faecium CHEMBL357 | EC50 | 6.0 | 6.0 | 990.0 | 1 |
| GroEL/GroES CHEMBL4106139 | IC50 | 5.66 | 5.515 | 2200.0 | 2 |
| Pancreatic triacylglycerol lipase CHEMBL1812 | IC50 | 5.6 | 5.6 | 2520.0 | 1 |
| HSP60/HSP10 CHEMBL4106131 | IC50 | 5.55 | 5.55 | 2800.0 | 1 |
| Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform CHEMBL4005 | IC50 | 4.88 | 4.88 | 13030.0 | 1 |
| Envelope glycoprotein gp160 CHEMBL1293311 | IC50 | 4.71 | 4.71 | 19700.0 | 1 |
| Acinetobacter baumannii CHEMBL614425 | EC50 | 4.51 | 4.51 | 31000.0 | 1 |
| Enterobacter cloacae CHEMBL349 | EC50 | 4.4 | 4.4 | 40000.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
Literature References
Data from ChEMBL 36 via Core Engine