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Assay Detail

CHEMBL3562123

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Functional
PubChem BioAssay. HT-29 viability from Cell TiterGlo-IC50. (Class of assay: confirmatory)
ChEMBL ↗
229
Total Activities
228
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Category confirmatory
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Target

Unchecked (CHEMBL612545) ↗
Type UNCHECKED

Publication

PubChem BioAssay data set

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 229 6.18 9.00

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL1981438 CLOFLUCARBAN 2.0 1 9.00
CHEMBL232201 BENZIODARONE 4.0 1 9.00
CHEMBL378544 VINBLASTINE SULFATE 4.0 2 9.00
CHEMBL3545252 DOCETAXEL 4.0 1 9.00
CHEMBL24944 TRIBROMSALAN 4.0 1 9.00
CHEMBL34259 METHOTREXATE 4.0 1 9.00
CHEMBL2360738 — — 1 8.52
CHEMBL3559830 — — 1 8.50
CHEMBL451887 CARFILZOMIB 4.0 1 8.50
CHEMBL81782 — — 1 8.08
CHEMBL287542 RAFOXANIDE 2.0 1 8.02
CHEMBL1545634 — — 1 8.01
CHEMBL50588 EMETINE 4.0 1 7.79
CHEMBL2361697 — — 1 7.73
CHEMBL2358886 — — 1 7.67
CHEMBL1607 TOPOTECAN HYDROCHLORIDE 4.0 1 7.61
CHEMBL105442 CI-1040 2.0 1 7.58
CHEMBL554041 ALEXIDINE DIHYDROCHLORIDE — 1 7.52
CHEMBL727 THIOGUANINE 4.0 1 7.31
CHEMBL448290 THIOINOSINE -1.0 1 6.93
CHEMBL12131 CLOSANTEL 2.0 1 6.90
CHEMBL98 VORINOSTAT 4.0 1 6.57
CHEMBL1076347 TRICLOCARBAN 2.0 1 6.42
CHEMBL1450 ATOVAQUONE 4.0 1 6.39
CHEMBL1375045 — — 1 6.39
CHEMBL3188653 — — 1 6.36
CHEMBL496 HEXACHLOROPHENE 4.0 1 6.34
CHEMBL64894 GENTIAN VIOLET 4.0 1 6.33
CHEMBL2355417 — — 1 6.33
CHEMBL388676 CAPTAN — 1 6.30

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL378544 VINBLASTINE SULFATE IC50 = 1.0 nM 9.00
CHEMBL24944 TRIBROMSALAN IC50 = 1.0 nM 9.00
CHEMBL232201 BENZIODARONE IC50 = 1.0 nM 9.00
CHEMBL1981438 CLOFLUCARBAN IC50 = 1.0 nM 9.00
CHEMBL378544 VINBLASTINE SULFATE IC50 = 1.0 nM 9.00
CHEMBL34259 METHOTREXATE IC50 = 1.0 nM 9.00
CHEMBL3545252 DOCETAXEL IC50 = 1.0 nM 9.00
CHEMBL2360738 — IC50 = 3.0 nM 8.52
CHEMBL3559830 — IC50 = 3.15 nM 8.50
CHEMBL451887 CARFILZOMIB IC50 = 3.18 nM 8.50
CHEMBL81782 — IC50 = 8.38 nM 8.08
CHEMBL287542 RAFOXANIDE IC50 = 9.5 nM 8.02
CHEMBL1545634 — IC50 = 9.82 nM 8.01
CHEMBL50588 EMETINE IC50 = 16.34 nM 7.79
CHEMBL2361697 — IC50 = 18.58 nM 7.73
CHEMBL2358886 — IC50 = 21.22 nM 7.67
CHEMBL1607 TOPOTECAN HYDROCHLORIDE IC50 = 24.64 nM 7.61
CHEMBL105442 CI-1040 IC50 = 26.34 nM 7.58
CHEMBL554041 ALEXIDINE DIHYDROCHLORIDE IC50 = 30.2 nM 7.52
CHEMBL727 THIOGUANINE IC50 = 49.27 nM 7.31
CHEMBL448290 THIOINOSINE IC50 = 118.09 nM 6.93
CHEMBL12131 CLOSANTEL IC50 = 125.5 nM 6.90
CHEMBL98 VORINOSTAT IC50 = 268.48 nM 6.57
CHEMBL1076347 TRICLOCARBAN IC50 = 383.3 nM 6.42
CHEMBL1375045 — IC50 = 409.1 nM 6.39
CHEMBL1450 ATOVAQUONE IC50 = 411.2 nM 6.39
CHEMBL3188653 — IC50 = 436.4 nM 6.36
CHEMBL496 HEXACHLOROPHENE IC50 = 459.6 nM 6.34
CHEMBL64894 GENTIAN VIOLET IC50 = 466.5 nM 6.33
CHEMBL2355417 — IC50 = 464.89 nM 6.33
CHEMBL388676 CAPTAN IC50 = 499.7 nM 6.30
CHEMBL550348 DEFERASIROX IC50 = 515.92 nM 6.29
CHEMBL1315136 TIBROFAN IC50 = 519.9 nM 6.28
CHEMBL1425 MERCAPTOPURINE ANHYDROUS IC50 = 634.55 nM 6.20
CHEMBL178 DAUNORUBICIN IC50 = 648.46 nM 6.19
CHEMBL2355158 — IC50 = 681.1 nM 6.17
CHEMBL86754 IODOQUINOL IC50 = 704.7 nM 6.15
CHEMBL1333953 PHENYLMERCURIC ACETATE IC50 = 798.9 nM 6.10
CHEMBL264373 METOPRINE IC50 = 931.65 nM 6.03
CHEMBL47050 PENFLURIDOL IC50 = 945.9 nM 6.02
CHEMBL290106 BITHIONOL IC50 = 995.9 nM 6.00
CHEMBL304432 NITROSCANATE IC50 = 1065.4 nM 5.97
CHEMBL1265 ADAPALENE IC50 = 1124.8 nM 5.95
CHEMBL388590 BENZBROMARONE IC50 = 1141.6 nM 5.94
CHEMBL1200563 CERIVASTATIN SODIUM IC50 = 1211.61 nM 5.92
CHEMBL5219790 CETRIMIDE IC50 = 1319.95 nM 5.88
CHEMBL449782 CEPHARANTHINE IC50 = 1364.52 nM 5.87
CHEMBL51483 GOSSYPOL IC50 = 1423.7 nM 5.85
CHEMBL3184339 — IC50 = 1442.9 nM 5.84
CHEMBL1200485 SORAFENIB TOSYLATE IC50 = 1463.7 nM 5.83