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Compound Detail

CHEMBL1315136

TIBROFAN
🧪 Phase II
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🧪 Phase II
O=C(Nc1ccc(Br)cc1)c1cc(Br)c(Br)s1

Basic Information

ChEMBL ID CHEMBL1315136
Name TIBROFAN
Phase Phase II
Structure Type MOL
InChI Key ZLWLKVQCHZSSEL-UHFFFAOYSA-N

Known Names

Tibrofan
1
Targets
8
Activities
1
Assay Types
0
PK Parameters
0
Publications
1
Known Names

Molecular Properties

439.9
MW (Da)
5.29
ALogP
2
HBA
1
HBD
29.1
PSA (Ų)
0.68
QED
1
Ro5 Violations
2
Rot. Bonds

Drug Information

Molecule Type Small molecule
Chirality Achiral
USAN Year 1967

Extended Properties

Molecular Formula C11H6Br3NOS
MW 439.95
Aromatic Rings 2
Heavy Atoms 17
NP-Likeness -1.84

Activity Summary

IC50 8 meas. best 7.75

Target Activity Profile

Target Type Best pChEMBL Mean pChEMBL Best (nM) # Data
Unchecked
CHEMBL612545
IC50 7.75 6.56 18.0 8

Activity Data Samples

Top measurements by pChEMBL value

Data from ChEMBL 36 via Core Engine