Fatty acid synthase · SINGLE PROTEIN · Gallus gallus
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As of 2026-09-14Protein identity stays anchored to UniProt P12276. Use UniProt P12276 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P12276 as the stable identity anchor, then attach disease evidence before program review.
Fatty acid synthase
Review this target as Fatty acid synthase, mapped to UniProt P12276. Sequence length is 2512 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Fatty acid synthase as ChEMBL target CHEMBL1795136, mapped to UniProt P12276. Disease framing currently uses the Open Targets-ready proxy contract.
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Start here when your first question is whether Fatty acid synthase is the right protein anchor across sources, using UniProt P12276 as the stable mapping.
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| Preferred Name | Fatty acid synthase |
| Target Type | SINGLE PROTEIN |
| Organism | Gallus gallus |
| UniProt | P12276 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Fatty acid synthase |
| UniProt Accession | P12276 |
| Component Type | Protein |
| Sequence Length | 2512 aa |
Fatty acid synthase
Review this target as Fatty acid synthase, mapped to UniProt P12276. Sequence length is 2512 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL471282 | 5.21 | IC50 | 6150.0 | Preclinical |
| CHEMBL123040 | 5.08 | IC50 | 8370.0 | Preclinical |
| CHEMBL1808693 | 4.9 | IC50 | 12700.0 | Preclinical |
| CHEMBL169 | 4.88 | IC50 | 13100.0 | Clinical |
| CHEMBL5266900 | 4.81 | IC50 | 15600.0 | Preclinical |
| CHEMBL5269517 | 4.81 | IC50 | 15600.0 | Preclinical |
| CHEMBL5271377 | 4.81 | IC50 | 15600.0 | Preclinical |
| CHEMBL5274276 | 4.81 | IC50 | 15600.0 | Preclinical |
| CHEMBL5283434 | 4.81 | IC50 | 15600.0 | Preclinical |
| CHEMBL2165410 | 4.8 | IC50 | 16000.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| assay format | 4 | 9 | 4.5 |
| single protein format | 1 | 1 | 4.9 |
| tissue-based format | 1 | 5 | 4.8 |