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Target Snapshot

CHEMBL1795169 Target Snapshot

Neuraminidase · SINGLE PROTEIN · Influenza A virus (strain A/Brevig Mission/1/1918 H1N1) (Influenza Avirus (strain A/South Carolina/1/1918 H1N1))

19Compounds
11Assays
2Approved Drugs
27.0Activities
Free Research Context

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Broader Open DB context

Frame the target before identity details

Structured disease, protein, and project context should read before the lower-level identity rail.

As of 2026-09-14

Protein identity stays anchored to UniProt Q9IGQ6. Use UniProt Q9IGQ6 as the stable identity anchor, then attach disease evidence before program review.

Review focus
Protein anchor ready

Use UniProt Q9IGQ6 as the stable identity anchor, then attach disease evidence before program review.

ChEMBL component mapping + Open Targets-ready proxy + ChEMBL 36 via Core Engine 2026-09-14
Open source guide
Identity Layer

Cross-source identity

Keep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.

This review treats Neuraminidase as ChEMBL target CHEMBL1795169, mapped to UniProt Q9IGQ6. Disease framing currently uses the Open Targets-ready proxy contract.

Review anchor
Neuraminidase
SINGLE PROTEIN · Influenza A virus (strain A/Brevig Mission/1/1918 H1N1) (Influenza Avirus (strain A/South Carolina/1/1918 H1N1))
As of 2026-09-14
ChEMBL target ID
CHEMBL1795169
Primary anchor for compounds, assays, approvals, and exports
ChEMBL 36 via Core Engine As of 2026-09-14
www.ebi.ac.uk
UniProt accession
Q9IGQ6
Neuraminidase
UniProt accession via ChEMBL component mapping As of 2026-09-14
www.uniprot.org
Disease evidence contract
Open Targets-ready proxy
ChEMBL drug mechanism + indication proxy
ChEMBL drug mechanism + indication proxy As of 2026-09-14
www.ebi.ac.uk

Reuse the same identifiers in notes, watch rules, exports, and review packs so provenance stays stable across surfaces.

Source Guidance

Start with the right source

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Need stable target naming and protein identity?
UniProt Target Context
UniProt accession via ChEMBL component mapping

Start here when your first question is whether Neuraminidase is the right protein anchor across sources, using UniProt Q9IGQ6 as the stable mapping.

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Disease Relevance & Evidence Level
ChEMBL drug mechanism + indication proxy

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Evidence Card
Review-ready rationale with source-aware context

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Overview

Basic Information

Verify identity, organism, and the fastest next research jumps from the same page.

UniProt Context

UniProt Target Context

Reviewable protein naming and mapping context for this target snapshot.

Protein LabelNeuraminidase
UniProt AccessionQ9IGQ6
Component TypeProtein
Sequence Length469 aa

Neuraminidase

Source · UniProt accession via ChEMBL component mapping
Review Cue

How to read this target

Review this target as Neuraminidase, mapped to UniProt Q9IGQ6. Sequence length is 469 aa.

Mapped IDQ9IGQ6
Review nameNeuraminidase
OrganismInfluenza A virus (strain A/Brevig Mission/1/1918 H1N1) (Influenza Avirus (strain A/South Carolina/1/1918 H1N1))
Clinical Profile

Clinical Phase Distribution

2
Approved
Assay Mix

Activity Type Distribution

IC5019.0
KI8.0
Lead Set

Top Inhibitors (by pChEMBL)

ChEMBL IDpChEMBLTypeValue (nM)Phase
CHEMBL139367 9.08 Ki 0.83 Approved
CHEMBL139367 8.47 IC50 3.4 Approved
CHEMBL1928608 8.12 Ki 7.5 Preclinical
CHEMBL1928608 7.75 IC50 17.7 Preclinical
CHEMBL1711961 4.91 IC50 12300.0 Preclinical
CHEMBL1711961 4.85 Ki 14000.0 Preclinical
CHEMBL1823414 4.7 Ki 20000.0 Preclinical
CHEMBL494082 4.68 Ki 20700.0 Preclinical
CHEMBL494082 4.65 IC50 22500.0 Preclinical
CHEMBL1823414 4.62 IC50 24200.0 Preclinical
Distribution

pChEMBL Value Distribution

0
5.0
0
5.5
0
6.0
0
6.5
0
7.0
1
7.5
2
8.0
0
8.5
1
9.0
0
9.5
pChEMBL
Approved Drugs

Approved Drugs

PERAMIVIR ANHYDROUS
CHEMBL139367
Approved 2014
Assay Landscape

Assay Landscape

11
Total Assays
16
Tested Compounds
1
Assay Types
Binding — 11 assays, 16 compounds
BAO Format Assays Compounds Avg pChEMBL
single protein format 11 16 5.2

Confidence Score Distribution

Source · ChEMBL 36 via Core Engine