Glycogen synthase kinase 3 beta · SINGLE PROTEIN · Sus scrofa
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As of 2026-09-14Protein identity stays anchored to UniProt B2LUN4. Use UniProt B2LUN4 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt B2LUN4 as the stable identity anchor, then attach disease evidence before program review.
Glycogen synthase kinase-3 beta
Review this target as Glycogen synthase kinase 3 beta, mapped to UniProt B2LUN4. ChEMBL maps the protein component as Glycogen synthase kinase-3 beta. Sequence length is 420 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Glycogen synthase kinase 3 beta as ChEMBL target CHEMBL1909485, mapped to UniProt B2LUN4. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Glycogen synthase kinase 3 beta |
| Target Type | SINGLE PROTEIN |
| Organism | Sus scrofa |
| UniProt | B2LUN4 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Glycogen synthase kinase-3 beta |
| UniProt Accession | B2LUN4 |
| Component Type | Protein |
| Sequence Length | 420 aa |
Glycogen synthase kinase-3 beta
Review this target as Glycogen synthase kinase 3 beta, mapped to UniProt B2LUN4. ChEMBL maps the protein component as Glycogen synthase kinase-3 beta. Sequence length is 420 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL409450 | 8.3 | IC50 | 5.0 | Preclinical |
| CHEMBL2321952 | 7.16 | IC50 | 70.0 | Preclinical |
| CHEMBL2321961 | 7.0 | IC50 | 100.0 | Preclinical |
| CHEMBL2321948 | 6.7 | IC50 | 200.0 | Preclinical |
| CHEMBL2321951 | 6.4 | IC50 | 400.0 | Preclinical |
| CHEMBL2321964 | 6.4 | IC50 | 400.0 | Preclinical |
| CHEMBL2321965 | 6.22 | IC50 | 600.0 | Preclinical |
| CHEMBL1910195 | 5.96 | IC50 | 1100.0 | Preclinical |
| CHEMBL1910197 | 5.96 | IC50 | 1100.0 | Preclinical |
| CHEMBL2321968 | 5.96 | IC50 | 1100.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| assay format | 3 | 23 | 5.8 |
| single protein format | 1 | 0 | — |