Use UniProt P49681 as the stable identity anchor, then attach disease evidence before program review.
CHEMBL1938219 Target Snapshot
Neuropeptides B/W receptor type 1 · SINGLE PROTEIN · Mus musculus
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As of 2026-09-14Protein identity stays anchored to UniProt P49681. Use UniProt P49681 as the stable identity anchor, then attach disease evidence before program review.
Neuropeptides B/W receptor type 1
Review this target as Neuropeptides B/W receptor type 1, mapped to UniProt P49681. Sequence length is 329 aa.
Protein source · UniProt accession via ChEMBL component mappingCross-source identity
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This review treats Neuropeptides B/W receptor type 1 as ChEMBL target CHEMBL1938219, mapped to UniProt P49681. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Neuropeptides B/W receptor type 1 |
| Target Type | SINGLE PROTEIN |
| Organism | Mus musculus |
| UniProt | P49681 |
Next Actions
UniProt Target Context
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Neuropeptides B/W receptor type 1 |
| UniProt Accession | P49681 |
| Component Type | Protein |
| Sequence Length | 329 aa |
Neuropeptides B/W receptor type 1
How to read this target
Review this target as Neuropeptides B/W receptor type 1, mapped to UniProt P49681. Sequence length is 329 aa.
Activity Type Distribution
Top Inhibitors (by pChEMBL)
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL1938418 | 9.74 | IC50 | 0.18 | Preclinical |
| CHEMBL1940544 | 9.7 | IC50 | 0.2 | Preclinical |
| CHEMBL1940540 | 9.48 | IC50 | 0.33 | Preclinical |
| CHEMBL1940545 | 9.38 | IC50 | 0.42 | Preclinical |
| CHEMBL1940543 | 9.37 | IC50 | 0.43 | Preclinical |
| CHEMBL1940537 | 9.16 | IC50 | 0.69 | Preclinical |
| CHEMBL1940539 | 8.96 | IC50 | 1.1 | Preclinical |
| CHEMBL1940536 | 8.72 | IC50 | 1.9 | Preclinical |
| CHEMBL1940541 | 8.66 | IC50 | 2.2 | Preclinical |
| CHEMBL1940538 | 8.62 | IC50 | 2.4 | Preclinical |
pChEMBL Value Distribution
Assay Landscape
Binding — 1 assays, 37 compounds
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 1 | 37 | 7.8 |
Functional — 1 assays, 40 compounds
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 1 | 40 | 6.9 |