Mitochondrial peptide methionine sulfoxide reductase · SINGLE PROTEIN · Bos taurus
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As of 2026-09-13Protein identity stays anchored to UniProt P54149. Use UniProt P54149 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P54149 as the stable identity anchor, then attach disease evidence before program review.
Mitochondrial peptide methionine sulfoxide reductase
Review this target as Mitochondrial peptide methionine sulfoxide reductase, mapped to UniProt P54149. Sequence length is 233 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Mitochondrial peptide methionine sulfoxide reductase as ChEMBL target CHEMBL2007622, mapped to UniProt P54149. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Mitochondrial peptide methionine sulfoxide reductase |
| Target Type | SINGLE PROTEIN |
| Organism | Bos taurus |
| UniProt | P54149 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Mitochondrial peptide methionine sulfoxide reductase |
| UniProt Accession | P54149 |
| Component Type | Protein |
| Sequence Length | 233 aa |
Mitochondrial peptide methionine sulfoxide reductase
Review this target as Mitochondrial peptide methionine sulfoxide reductase, mapped to UniProt P54149. Sequence length is 233 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL1497838 | 5.67 | EC50 | 2127.0 | Preclinical |
| CHEMBL1485159 | 5.45 | EC50 | 3534.0 | Preclinical |
| CHEMBL235504 | 5.44 | EC50 | 3637.0 | Preclinical |
| CHEMBL417727 | 5.04 | EC50 | 9088.0 | Preclinical |
| CHEMBL1870250 | 4.99 | EC50 | 10330.0 | Preclinical |
| CHEMBL1887807 | 4.89 | EC50 | 12900.0 | Preclinical |
| CHEMBL1728280 | 4.85 | EC50 | 14085.0 | Preclinical |
| CHEMBL1489745 | 4.8 | EC50 | 15803.0 | Preclinical |
| CHEMBL2373711 | 4.8 | EC50 | 15779.0 | Preclinical |
| CHEMBL1613638 | 4.76 | EC50 | 17416.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| assay format | 2 | 42 | 4.5 |