Compound Detail
CHEMBL1497838
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Basic Information
| ChEMBL ID | CHEMBL1497838 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | CGKNQKTUUZILFY-UHFFFAOYSA-N |
| Parent Compound | CHEMBL1622746 |
| Active Moiety | CHEMBL1622746 |
8
Targets
16
Activities
2
Assay Types
0
PK Parameters
0
Publications
0
Known Names
Molecular Properties
224.3
MW (Da)
2.25
ALogP
2
HBA
1
HBD
28.8
PSA (Ų)
0.51
QED
0
Ro5 Violations
1
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 10 meas. best 5.94
EC50 6 meas. best 6.16
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Unchecked CHEMBL612545 | EC50 | 6.16 | 5.92 | 689.0 | 2 |
| Unchecked CHEMBL612545 | IC50 | 5.94 | 5.23 | 1160.0 | 6 |
| Mitochondrial peptide methionine sulfoxide reductase CHEMBL2007622 | EC50 | 5.67 | 5.67 | 2127.0 | 1 |
| Protein RecA CHEMBL1741171 | EC50 | 5.62 | 5.62 | 2370.0 | 1 |
| Apoptotic protease-activating factor 1 CHEMBL1795093 | IC50 | 4.94 | 4.94 | 11500.0 | 1 |
| Matrix metalloproteinase-14 CHEMBL3869 | IC50 | 4.85 | 4.85 | 14000.0 | 1 |
| Zinc finger protein mex-5 CHEMBL1293319 | EC50 | 4.83 | 4.83 | 14832.0 | 1 |
| Polyadenylate-binding protein 1 CHEMBL1293286 | IC50 | 4.75 | 4.605 | 18000.0 | 2 |
| RNA-binding protein pos-1 CHEMBL1293304 | EC50 | 4.69 | 4.69 | 20503.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
Data from ChEMBL 36 via Core Engine