Polyadenylate-binding protein 1 · SINGLE PROTEIN · Homo sapiens
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As of 2026-09-13Protein identity stays anchored to UniProt P11940. Use UniProt P11940 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P11940 as the stable identity anchor, then attach disease evidence before program review.
Polyadenylate-binding protein 1
Review this target as Polyadenylate-binding protein 1, mapped to UniProt P11940. Sequence length is 636 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Polyadenylate-binding protein 1 as ChEMBL target CHEMBL1293286, mapped to UniProt P11940. Disease framing currently uses the Open Targets-ready proxy contract.
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Start here when your first question is whether Polyadenylate-binding protein 1 is the right protein anchor across sources, using UniProt P11940 as the stable mapping.
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| Preferred Name | Polyadenylate-binding protein 1 |
| Target Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
| UniProt | P11940 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Polyadenylate-binding protein 1 |
| UniProt Accession | P11940 |
| Component Type | Protein |
| Sequence Length | 636 aa |
Polyadenylate-binding protein 1
Review this target as Polyadenylate-binding protein 1, mapped to UniProt P11940. Sequence length is 636 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL1497773 | 5.88 | IC50 | 1320.0 | Preclinical |
| CHEMBL1545487 | 5.88 | IC50 | 1330.0 | Preclinical |
| CHEMBL1464460 | 5.78 | IC50 | 1680.0 | Preclinical |
| CHEMBL592588 | 5.73 | IC50 | 1870.0 | Preclinical |
| CHEMBL1423915 | 5.73 | IC50 | 1850.0 | Preclinical |
| CHEMBL589711 | 5.65 | IC50 | 2220.0 | Preclinical |
| CHEMBL1383779 | 5.61 | IC50 | 2480.0 | Preclinical |
| CHEMBL1577127 | 5.57 | IC50 | 2725.0 | Preclinical |
| CHEMBL1445700 | 5.56 | IC50 | 2760.0 | Preclinical |
| CHEMBL1463019 | 5.55 | IC50 | 2790.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 8 | 130 | 5.0 |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| assay format | 4 | 209 | 4.5 |