Compound Detail
CHEMBL592588
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Basic Information
| ChEMBL ID | CHEMBL592588 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | UKQREQQAILHJBS-UHFFFAOYSA-M |
| Parent Compound | CHEMBL1197985 |
| Active Moiety | CHEMBL1197985 |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
285.4
MW (Da)
2.51
ALogP
3
HBA
1
HBD
27.4
PSA (Ų)
0.88
QED
0
Ro5 Violations
3
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 5.73
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Polyadenylate-binding protein 1 CHEMBL1293286 | IC50 | 5.73 | 5.73 | 1870.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Polyadenylate-binding protein 1 | IC50 | = | 1870.0 | nM | 5.73 | PUBCHEM_BIOASSAY: uHTS fluorescence polarization assay for the identification of... | - |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 20485428 | 10.1038/nature09099 | Plasmodium falciparum | 2 |
Data from ChEMBL 36 via Core Engine