Compound Detail
CHEMBL1464460
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Basic Information
| ChEMBL ID | CHEMBL1464460 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | PSVMJGYZQLPLNM-UHFFFAOYSA-N |
2
Targets
3
Activities
1
Assay Types
0
PK Parameters
0
Publications
0
Known Names
Molecular Properties
282.7
MW (Da)
4.14
ALogP
2
HBA
1
HBD
42.0
PSA (Ų)
0.77
QED
0
Ro5 Violations
2
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 3 meas. best 5.78
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Polyadenylate-binding protein 1 CHEMBL1293286 | IC50 | 5.78 | 5.59 | 1680.0 | 2 |
| Eukaryotic translation initiation factor 4H CHEMBL1293274 | IC50 | 5.03 | 5.03 | 9250.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Polyadenylate-binding protein 1 | IC50 | = | 1680.0 | nM | 5.78 | PUBCHEM_BIOASSAY: SAR analysis for the identification of translation initiation ... | - |
| Polyadenylate-binding protein 1 | IC50 | = | 4000.0 | nM | 5.4 | PUBCHEM_BIOASSAY: uHTS fluorescence polarization assay for the identification of... | - |
| Eukaryotic translation initiation factor 4H | IC50 | = | 9250.0 | nM | 5.03 | PUBCHEM_BIOASSAY: SAR analysis for the identification of translation initiation ... | - |
Data from ChEMBL 36 via Core Engine