Eukaryotic translation initiation factor 4H · SINGLE PROTEIN · Homo sapiens
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Structured disease, protein, and project context should read before the lower-level identity rail.
As of 2026-09-14Protein identity stays anchored to UniProt Q15056. Use UniProt Q15056 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt Q15056 as the stable identity anchor, then attach disease evidence before program review.
Eukaryotic translation initiation factor 4H
Review this target as Eukaryotic translation initiation factor 4H, mapped to UniProt Q15056. Sequence length is 248 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Eukaryotic translation initiation factor 4H as ChEMBL target CHEMBL1293274, mapped to UniProt Q15056. Disease framing currently uses the Open Targets-ready proxy contract.
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Start here when your first question is whether Eukaryotic translation initiation factor 4H is the right protein anchor across sources, using UniProt Q15056 as the stable mapping.
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| Preferred Name | Eukaryotic translation initiation factor 4H |
| Target Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
| UniProt | Q15056 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Eukaryotic translation initiation factor 4H |
| UniProt Accession | Q15056 |
| Component Type | Protein |
| Sequence Length | 248 aa |
Eukaryotic translation initiation factor 4H
Review this target as Eukaryotic translation initiation factor 4H, mapped to UniProt Q15056. Sequence length is 248 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL1542453 | 6.16 | IC50 | 700.0 | Preclinical |
| CHEMBL1497773 | 5.94 | IC50 | 1140.0 | Preclinical |
| CHEMBL1522300 | 5.84 | IC50 | 1430.0 | Preclinical |
| CHEMBL3190268 | 5.64 | IC50 | 2310.0 | Preclinical |
| CHEMBL1344772 | 5.62 | IC50 | 2410.0 | Preclinical |
| CHEMBL3856090 | 5.58 | IC50 | 2660.0 | Preclinical |
| CHEMBL1703699 | 5.56 | IC50 | 2740.0 | Preclinical |
| CHEMBL1420111 | 5.53 | IC50 | 2935.0 | Preclinical |
| CHEMBL1445700 | 5.37 | IC50 | 4230.0 | Preclinical |
| CHEMBL1583797 | 5.33 | IC50 | 4620.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 2 | 74 | 4.7 |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| assay format | 1 | 43 | 4.8 |