Compound Detail
CHEMBL1545487
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CCN1CCN(S(=O)(=O)c2ccc(Cl)c(C(=O)Nc3ccc(C(=O)N(CC)CC)cc3)c2)CC1
Basic Information
| ChEMBL ID | CHEMBL1545487 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | ZILCYCGGNNYUQQ-UHFFFAOYSA-N |
1
Targets
2
Activities
1
Assay Types
0
PK Parameters
0
Publications
0
Known Names
Molecular Properties
507.1
MW (Da)
3.40
ALogP
5
HBA
1
HBD
90.0
PSA (Ų)
0.59
QED
1
Ro5 Violations
8
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 2 meas. best 5.88
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Polyadenylate-binding protein 1 CHEMBL1293286 | IC50 | 5.88 | 5.35 | 1330.0 | 2 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Polyadenylate-binding protein 1 | IC50 | = | 1330.0 | nM | 5.88 | PUBCHEM_BIOASSAY: SAR analysis for the identification of translation initiation ... | - |
| Polyadenylate-binding protein 1 | IC50 | = | 15075.0 | nM | 4.82 | PUBCHEM_BIOASSAY: uHTS fluorescence polarization assay for the identification of... | - |
Data from ChEMBL 36 via Core Engine