Use UniProt Q63344 as the stable identity anchor, then attach disease evidence before program review.
CHEMBL2073718 Target Snapshot
Monocarboxylate transporter 2 · SINGLE PROTEIN · Rattus norvegicus
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As of 2026-09-13Protein identity stays anchored to UniProt Q63344. Use UniProt Q63344 as the stable identity anchor, then attach disease evidence before program review.
Monocarboxylate transporter 2
Review this target as Monocarboxylate transporter 2, mapped to UniProt Q63344. Sequence length is 489 aa.
Protein source · UniProt accession via ChEMBL component mappingCross-source identity
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This review treats Monocarboxylate transporter 2 as ChEMBL target CHEMBL2073718, mapped to UniProt Q63344. Disease framing currently uses the Open Targets-ready proxy contract.
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Start here when your first question is whether Monocarboxylate transporter 2 is the right protein anchor across sources, using UniProt Q63344 as the stable mapping.
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Open Review-ready CardBasic Information
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| Preferred Name | Monocarboxylate transporter 2 |
| Target Type | SINGLE PROTEIN |
| Organism | Rattus norvegicus |
| UniProt | Q63344 |
Next Actions
UniProt Target Context
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Monocarboxylate transporter 2 |
| UniProt Accession | Q63344 |
| Component Type | Protein |
| Sequence Length | 489 aa |
Monocarboxylate transporter 2
How to read this target
Review this target as Monocarboxylate transporter 2, mapped to UniProt Q63344. Sequence length is 489 aa.
Clinical Phase Distribution
Activity Type Distribution
Top Inhibitors (by pChEMBL)
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL50 | 5.3 | IC50 | 5000.0 | Clinical |
| CHEMBL388590 | 5.05 | IC50 | 9000.0 | Approved |
| CHEMBL45068 | 4.85 | IC50 | 14000.0 | Preclinical |
| CHEMBL76602 | 4.62 | IC50 | 24000.0 | Preclinical |
| CHEMBL1162144 | 4.1 | Ki | 80000.0 | Clinical |
| CHEMBL445647 | 4.0 | Ki | 100000.0 | Preclinical |
pChEMBL Value Distribution
Assay Landscape
Binding — 2 assays, 0 compounds
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 2 | 0 | — |
Functional — 1 assays, 9 compounds
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 1 | 9 | 4.7 |