Angiotensin II receptor · PROTEIN FAMILY · Homo sapiens
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As of 2026-09-14Protein identity stays anchored to UniProt P30556. Use UniProt P30556 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P30556 as the stable identity anchor, then attach disease evidence before program review.
Type-1 angiotensin II receptor
Review this target as Angiotensin II receptor, mapped to UniProt P30556. ChEMBL maps the protein component as Type-1 angiotensin II receptor. Sequence length is 359 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Angiotensin II receptor as ChEMBL target CHEMBL2094256, mapped to UniProt P30556. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Angiotensin II receptor |
| Target Type | PROTEIN FAMILY |
| Organism | Homo sapiens |
| UniProt | P30556 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Type-1 angiotensin II receptor |
| UniProt Accession | P30556 |
| Component Type | Protein |
| Sequence Length | 359 aa |
Type-1 angiotensin II receptor
Review this target as Angiotensin II receptor, mapped to UniProt P30556. ChEMBL maps the protein component as Type-1 angiotensin II receptor. Sequence length is 359 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL47177 | 10.9 | Kd | 0.01259 | Preclinical |
| CHEMBL416477 | 10.7 | Kd | 0.01995 | Preclinical |
| CHEMBL125218 | 10.33 | Kd | 0.04677 | Preclinical |
| CHEMBL293511 | 10.3 | Kd | 0.05012 | Preclinical |
| CHEMBL418226 | 10.3 | Kd | 0.05012 | Preclinical |
| CHEMBL92542 | 10.25 | Kd | 0.05623 | Preclinical |
| CHEMBL938 | 10.18 | IC50 | 0.066 | Approved |
| CHEMBL295854 | 10.1 | IC50 | 0.08 | Preclinical |
| CHEMBL907 | 10.09 | Kd | 0.08128 | Preclinical |
| CHEMBL41194 | 10.04 | Kd | 0.0912 | Clinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| tissue-based format | 28 | 231 | 7.8 |
| assay format | 4 | 11 | 8.6 |
| organism-based format | 4 | 0 | — |
| cell-based format | 1 | 9 | 7.6 |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| protein format | 20 | 57 | 8.1 |
| tissue-based format | 5 | 120 | 8.2 |
| assay format | 3 | 44 | 7.6 |
| cell membrane format | 2 | 23 | 5.4 |