Opioid receptors; mu & delta · SELECTIVITY GROUP · Homo sapiens
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As of 2026-09-14Protein identity stays anchored to UniProt P41143. Use UniProt P41143 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P41143 as the stable identity anchor, then attach disease evidence before program review.
Delta-type opioid receptor
Review this target as Opioid receptors; mu & delta, mapped to UniProt P41143. ChEMBL maps the protein component as Delta-type opioid receptor. Sequence length is 372 aa.
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This review treats Opioid receptors; mu & delta as ChEMBL target CHEMBL2095149, mapped to UniProt P41143. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Opioid receptors; mu & delta |
| Target Type | SELECTIVITY GROUP |
| Organism | Homo sapiens |
| UniProt | P41143 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Delta-type opioid receptor |
| UniProt Accession | P41143 |
| Component Type | Protein |
| Sequence Length | 372 aa |
Delta-type opioid receptor
Review this target as Opioid receptors; mu & delta, mapped to UniProt P41143. ChEMBL maps the protein component as Delta-type opioid receptor. Sequence length is 372 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL19019 | 10.7 | Ki | 0.02 | Approved |
| CHEMBL2370601 | 10.3 | IC50 | 0.05 | Preclinical |
| CHEMBL109040 | 10.1 | Ki | 0.08 | Preclinical |
| CHEMBL127378 | 9.82 | IC50 | 0.15 | Preclinical |
| CHEMBL125564 | 9.6 | IC50 | 0.25 | Preclinical |
| CHEMBL108608 | 9.4 | Ki | 0.4 | Preclinical |
| CHEMBL124283 | 9.4 | IC50 | 0.4 | Preclinical |
| CHEMBL127711 | 9.39 | IC50 | 0.41 | Preclinical |
| CHEMBL107420 | 9.22 | Ki | 0.6 | Preclinical |
| CHEMBL110124 | 9.1 | Ki | 0.8 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| protein format | 104 | 10 | 9.0 |
| tissue-based format | 3 | 0 | — |
| assay format | 2 | 0 | — |
| cell membrane format | 2 | 8 | 6.6 |
| cell-based format | 2 | 0 | — |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| assay format | 9 | 0 | — |
| cell-based format | 9 | 208 | 5.2 |
| cell membrane format | 3 | 19 | 7.0 |
| tissue-based format | 1 | 23 | 7.7 |