Exodeoxyribonuclease V · PROTEIN COMPLEX · Escherichia coli (strain K12)
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As of 2026-09-14Protein identity stays anchored to UniProt P04993. Use UniProt P04993 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P04993 as the stable identity anchor, then attach disease evidence before program review.
RecBCD enzyme subunit RecD
Review this target as Exodeoxyribonuclease V, mapped to UniProt P04993. ChEMBL maps the protein component as RecBCD enzyme subunit RecD. Sequence length is 608 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Exodeoxyribonuclease V as ChEMBL target CHEMBL2095232, mapped to UniProt P04993. Disease framing currently uses the Open Targets-ready proxy contract.
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Start here when your first question is whether Exodeoxyribonuclease V is the right protein anchor across sources, using UniProt P04993 as the stable mapping.
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| Preferred Name | Exodeoxyribonuclease V |
| Target Type | PROTEIN COMPLEX |
| Organism | Escherichia coli (strain K12) |
| UniProt | P04993 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | RecBCD enzyme subunit RecD |
| UniProt Accession | P04993 |
| Component Type | Protein |
| Sequence Length | 608 aa |
RecBCD enzyme subunit RecD
Review this target as Exodeoxyribonuclease V, mapped to UniProt P04993. ChEMBL maps the protein component as RecBCD enzyme subunit RecD. Sequence length is 608 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL1729758 | 4.82 | IC50 | 15157.0 | Preclinical |
| CHEMBL1396209 | 4.7 | IC50 | 20120.0 | Preclinical |
| CHEMBL1989750 | 4.56 | IC50 | 27479.0 | Preclinical |
| CHEMBL1546374 | 4.55 | IC50 | 28433.0 | Preclinical |
| CHEMBL415879 | 4.52 | IC50 | 30473.0 | Preclinical |
| CHEMBL1431189 | 4.36 | IC50 | 44011.0 | Preclinical |
| CHEMBL1557648 | 4.35 | IC50 | 44242.0 | Preclinical |
| CHEMBL1528900 | 4.25 | IC50 | 56272.0 | Preclinical |
| CHEMBL1967099 | 4.25 | IC50 | 56351.0 | Preclinical |
| CHEMBL3194449 | 4.24 | IC50 | 57133.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 1 | 25 | 4.3 |