Phosphatidylinositol 4-kinase, PI4K · PROTEIN FAMILY · Homo sapiens
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As of 2026-09-13Protein identity stays anchored to UniProt Q9BTU6. Use UniProt Q9BTU6 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt Q9BTU6 as the stable identity anchor, then attach disease evidence before program review.
Phosphatidylinositol 4-kinase type 2-alpha
Review this target as Phosphatidylinositol 4-kinase, PI4K, mapped to UniProt Q9BTU6. ChEMBL maps the protein component as Phosphatidylinositol 4-kinase type 2-alpha. Sequence length is 479 aa.
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This review treats Phosphatidylinositol 4-kinase, PI4K as ChEMBL target CHEMBL2096619, mapped to UniProt Q9BTU6. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Phosphatidylinositol 4-kinase, PI4K |
| Target Type | PROTEIN FAMILY |
| Organism | Homo sapiens |
| UniProt | Q9BTU6 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Phosphatidylinositol 4-kinase type 2-alpha |
| UniProt Accession | Q9BTU6 |
| Component Type | Protein |
| Sequence Length | 479 aa |
Phosphatidylinositol 4-kinase type 2-alpha
Review this target as Phosphatidylinositol 4-kinase, PI4K, mapped to UniProt Q9BTU6. ChEMBL maps the protein component as Phosphatidylinositol 4-kinase type 2-alpha. Sequence length is 479 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL63783 | 5.43 | Ki | 3700.0 | Preclinical |
| CHEMBL293027 | 5.39 | Ki | 4100.0 | Preclinical |
| CHEMBL413106 | 5.3 | Ki | 5000.0 | Preclinical |
| CHEMBL62835 | 5.3 | Ki | 5000.0 | Preclinical |
| CHEMBL293027 | 5.22 | IC50 | 6000.0 | Preclinical |
| CHEMBL63783 | 5.22 | IC50 | 6000.0 | Preclinical |
| CHEMBL294590 | 5.22 | Ki | 6000.0 | Preclinical |
| CHEMBL306444 | 5.16 | Ki | 6900.0 | Preclinical |
| CHEMBL21619 | 5.15 | IC50 | 7100.0 | Preclinical |
| CHEMBL413106 | 5.14 | IC50 | 7200.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| protein format | 8 | 53 | 4.6 |
| cell-based format | 2 | 0 | — |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| assay format | 2 | 0 | — |