Protein kinase C, PKC; classical/novel · PROTEIN FAMILY · Homo sapiens
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As of 2026-09-14Protein identity stays anchored to UniProt O94806. Use UniProt O94806 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt O94806 as the stable identity anchor, then attach disease evidence before program review.
Serine/threonine-protein kinase D3
Review this target as Protein kinase C, PKC; classical/novel, mapped to UniProt O94806. ChEMBL maps the protein component as Serine/threonine-protein kinase D3. Sequence length is 890 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Protein kinase C, PKC; classical/novel as ChEMBL target CHEMBL2096620, mapped to UniProt O94806. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Protein kinase C, PKC; classical/novel |
| Target Type | PROTEIN FAMILY |
| Organism | Homo sapiens |
| UniProt | O94806 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Serine/threonine-protein kinase D3 |
| UniProt Accession | O94806 |
| Component Type | Protein |
| Sequence Length | 890 aa |
Serine/threonine-protein kinase D3
Review this target as Protein kinase C, PKC; classical/novel, mapped to UniProt O94806. ChEMBL maps the protein component as Serine/threonine-protein kinase D3. Sequence length is 890 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL120645 | 6.82 | IC50 | 150.0 | Preclinical |
| CHEMBL170518 | 6.72 | Ki | 190.0 | Preclinical |
| CHEMBL422215 | 6.7 | Ki | 200.0 | Preclinical |
| CHEMBL143453 | 6.4 | IC50 | 400.0 | Preclinical |
| CHEMBL12988 | 6.22 | Ki | 600.0 | Preclinical |
| CHEMBL13306 | 6.22 | Ki | 600.0 | Preclinical |
| CHEMBL421565 | 6.22 | IC50 | 600.0 | Preclinical |
| CHEMBL1202927 | 5.7 | IC50 | 2000.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| protein format | 9 | 5 | 6.5 |
| cell-based format | 2 | 1 | 6.7 |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| assay format | 2 | 2 | 6.0 |