Use UniProt P21803 as the stable identity anchor, then attach disease evidence before program review.
CHEMBL2111391 Target Snapshot
Fibroblast growth factor receptor · PROTEIN FAMILY · Mus musculus
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As of 2026-09-14Protein identity stays anchored to UniProt P21803. Use UniProt P21803 as the stable identity anchor, then attach disease evidence before program review.
Fibroblast growth factor receptor 2
Review this target as Fibroblast growth factor receptor, mapped to UniProt P21803. ChEMBL maps the protein component as Fibroblast growth factor receptor 2. Sequence length is 821 aa.
Protein source · UniProt accession via ChEMBL component mappingCross-source identity
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This review treats Fibroblast growth factor receptor as ChEMBL target CHEMBL2111391, mapped to UniProt P21803. Disease framing currently uses the Open Targets-ready proxy contract.
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Start here when your first question is whether Fibroblast growth factor receptor is the right protein anchor across sources, using UniProt P21803 as the stable mapping.
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Open Review-ready CardBasic Information
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| Preferred Name | Fibroblast growth factor receptor |
| Target Type | PROTEIN FAMILY |
| Organism | Mus musculus |
| UniProt | P21803 |
Next Actions
UniProt Target Context
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Fibroblast growth factor receptor 2 |
| UniProt Accession | P21803 |
| Component Type | Protein |
| Sequence Length | 821 aa |
Fibroblast growth factor receptor 2
How to read this target
Review this target as Fibroblast growth factor receptor, mapped to UniProt P21803. ChEMBL maps the protein component as Fibroblast growth factor receptor 2. Sequence length is 821 aa.
Clinical Phase Distribution
Activity Type Distribution
Top Inhibitors (by pChEMBL)
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL112914 | 7.52 | IC50 | 30.0 | Preclinical |
| CHEMBL49120 | 7.37 | IC50 | 43.0 | Preclinical |
| CHEMBL136106 | 7.06 | IC50 | 88.0 | Preclinical |
| CHEMBL336409 | 6.7 | IC50 | 200.0 | Preclinical |
| CHEMBL136244 | 6.46 | IC50 | 350.0 | Preclinical |
| CHEMBL136280 | 6.43 | IC50 | 370.0 | Preclinical |
| CHEMBL337157 | 6.3 | IC50 | 500.0 | Preclinical |
| CHEMBL136775 | 6.29 | IC50 | 510.0 | Preclinical |
| CHEMBL139249 | 6.27 | IC50 | 540.0 | Preclinical |
| CHEMBL138319 | 6.24 | IC50 | 580.0 | Preclinical |
pChEMBL Value Distribution
Assay Landscape
Functional — 4 assays, 7 compounds
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| assay format | 3 | 7 | 5.3 |
| cell-based format | 1 | 0 | — |
Binding — 1 assays, 23 compounds
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| protein format | 1 | 23 | 6.0 |