Diamine oxidase [copper-containing] · SINGLE PROTEIN · Homo sapiens
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As of 2026-09-14Protein identity stays anchored to UniProt P19801. Use UniProt P19801 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P19801 as the stable identity anchor, then attach disease evidence before program review.
Diamine oxidase [copper-containing]
Review this target as Diamine oxidase [copper-containing], mapped to UniProt P19801. Sequence length is 751 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Diamine oxidase [copper-containing] as ChEMBL target CHEMBL2118, mapped to UniProt P19801. Disease framing currently uses the Open Targets-ready proxy contract.
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Start here when your first question is whether Diamine oxidase [copper-containing] is the right protein anchor across sources, using UniProt P19801 as the stable mapping.
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| Preferred Name | Diamine oxidase [copper-containing] |
| Target Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
| UniProt | P19801 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Diamine oxidase [copper-containing] |
| UniProt Accession | P19801 |
| Component Type | Protein |
| Sequence Length | 751 aa |
Diamine oxidase [copper-containing]
Review this target as Diamine oxidase [copper-containing], mapped to UniProt P19801. Sequence length is 751 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL35241 | 7.89 | Ki | 13.0 | Clinical |
| CHEMBL534467 | 7.21 | IC50 | 61.0 | Preclinical |
| CHEMBL537845 | 6.92 | IC50 | 120.0 | Preclinical |
| CHEMBL225304 | 6.85 | Ki | 140.0 | Clinical |
| CHEMBL534914 | 6.8 | IC50 | 160.0 | Preclinical |
| CHEMBL330979 | 6.77 | Ki | 170.0 | Preclinical |
| CHEMBL119195 | 6.7 | Ki | 200.0 | Preclinical |
| CHEMBL55 | 6.54 | Ki | 290.0 | Approved |
| CHEMBL536953 | 6.52 | IC50 | 300.0 | Preclinical |
| CHEMBL537624 | 6.3 | IC50 | 500.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 10 | 24 | 5.7 |
| cell-based format | 1 | 2 | 7.2 |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| assay format | 1 | 1 | 4.8 |