Serine/threonine-protein phosphatase PP1-alpha catalytic subunit · SINGLE PROTEIN · Homo sapiens
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As of 2026-09-14Protein identity stays anchored to UniProt P62136. Use UniProt P62136 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P62136 as the stable identity anchor, then attach disease evidence before program review.
Serine/threonine-protein phosphatase PP1-alpha catalytic subunit
Review this target as Serine/threonine-protein phosphatase PP1-alpha catalytic subunit, mapped to UniProt P62136. Sequence length is 330 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Serine/threonine-protein phosphatase PP1-alpha catalytic subunit as ChEMBL target CHEMBL2164, mapped to UniProt P62136. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Serine/threonine-protein phosphatase PP1-alpha catalytic subunit |
| Target Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
| UniProt | P62136 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Serine/threonine-protein phosphatase PP1-alpha catalytic subunit |
| UniProt Accession | P62136 |
| Component Type | Protein |
| Sequence Length | 330 aa |
Serine/threonine-protein phosphatase PP1-alpha catalytic subunit
Review this target as Serine/threonine-protein phosphatase PP1-alpha catalytic subunit, mapped to UniProt P62136. Sequence length is 330 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL1344034 | 6.64 | IC50 | 227.35 | Preclinical |
| CHEMBL299846 | 6.57 | IC50 | 271.6 | Preclinical |
| CHEMBL1519313 | 5.71 | IC50 | 1971.0 | Preclinical |
| CHEMBL1530097 | 5.63 | IC50 | 2363.0 | Preclinical |
| CHEMBL1503729 | 5.61 | IC50 | 2477.0 | Preclinical |
| CHEMBL1533230 | 5.61 | IC50 | 2463.0 | Preclinical |
| CHEMBL567967 | 5.57 | IC50 | 2667.0 | Preclinical |
| CHEMBL1329288 | 5.55 | IC50 | 2846.0 | Preclinical |
| CHEMBL8327 | 5.55 | IC50 | 2832.0 | Preclinical |
| CHEMBL1455825 | 5.44 | IC50 | 3632.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 13 | 91 | 5.0 |
| cell-based format | 1 | 0 | — |