cGMP-dependent protein kinase · SINGLE PROTEIN · Plasmodium falciparum
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As of 2026-09-14Protein identity stays anchored to UniProt W7JX98. Use UniProt W7JX98 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt W7JX98 as the stable identity anchor, then attach disease evidence before program review.
cGMP-dependent protein kinase
Review this target as cGMP-dependent protein kinase, mapped to UniProt W7JX98. Sequence length is 853 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats cGMP-dependent protein kinase as ChEMBL target CHEMBL2169724, mapped to UniProt W7JX98. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | cGMP-dependent protein kinase |
| Target Type | SINGLE PROTEIN |
| Organism | Plasmodium falciparum |
| UniProt | W7JX98 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | cGMP-dependent protein kinase |
| UniProt Accession | W7JX98 |
| Component Type | Protein |
| Sequence Length | 853 aa |
cGMP-dependent protein kinase
Review this target as cGMP-dependent protein kinase, mapped to UniProt W7JX98. Sequence length is 853 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL5571745 | 9.8 | IC50 | 0.16 | Preclinical |
| CHEMBL4285682 | 9.52 | IC50 | 0.3 | Preclinical |
| CHEMBL4288816 | 9.3 | IC50 | 0.5 | Preclinical |
| CHEMBL4531058 | 9.22 | IC50 | 0.6 | Preclinical |
| CHEMBL4288103 | 9.15 | IC50 | 0.7 | Preclinical |
| CHEMBL4286880 | 9.05 | IC50 | 0.9 | Preclinical |
| CHEMBL4279865 | 9.0 | IC50 | 1.0 | Preclinical |
| CHEMBL4459320 | 8.89 | IC50 | 1.3 | Preclinical |
| CHEMBL4449947 | 8.77 | IC50 | 1.7 | Preclinical |
| CHEMBL4451783 | 8.77 | IC50 | 1.7 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 5 | 22 | 7.9 |
| cell-based format | 1 | 32 | 8.2 |