Use UniProt O95237 as the stable identity anchor, then attach disease evidence before program review.
CHEMBL2202 Target Snapshot
Lecithin retinol acyltransferase · SINGLE PROTEIN · Homo sapiens
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As of 2026-09-14Protein identity stays anchored to UniProt O95237. Use UniProt O95237 as the stable identity anchor, then attach disease evidence before program review.
Lecithin retinol acyltransferase
Review this target as Lecithin retinol acyltransferase, mapped to UniProt O95237. Sequence length is 230 aa.
Protein source · UniProt accession via ChEMBL component mappingCross-source identity
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This review treats Lecithin retinol acyltransferase as ChEMBL target CHEMBL2202, mapped to UniProt O95237. Disease framing currently uses the Open Targets-ready proxy contract.
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Start here when your first question is whether Lecithin retinol acyltransferase is the right protein anchor across sources, using UniProt O95237 as the stable mapping.
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Open Review-ready CardBasic Information
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| Preferred Name | Lecithin retinol acyltransferase |
| Target Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
| UniProt | O95237 |
Next Actions
UniProt Target Context
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Lecithin retinol acyltransferase |
| UniProt Accession | O95237 |
| Component Type | Protein |
| Sequence Length | 230 aa |
Lecithin retinol acyltransferase
How to read this target
Review this target as Lecithin retinol acyltransferase, mapped to UniProt O95237. Sequence length is 230 aa.
Clinical Phase Distribution
Activity Type Distribution
Top Inhibitors (by pChEMBL)
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL184618 | 4.83 | IC50 | 14900.0 | Clinical |
| CHEMBL427409 | 4.41 | IC50 | 38600.0 | Preclinical |
pChEMBL Value Distribution
Assay Landscape
Binding — 1 assays, 3 compounds
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 1 | 3 | 4.6 |