TAR DNA-binding protein 43 · SINGLE PROTEIN · Homo sapiens
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As of 2026-09-14Protein identity stays anchored to UniProt Q13148. Use UniProt Q13148 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt Q13148 as the stable identity anchor, then attach disease evidence before program review.
TAR DNA-binding protein 43
Review this target as TAR DNA-binding protein 43, mapped to UniProt Q13148. Sequence length is 414 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats TAR DNA-binding protein 43 as ChEMBL target CHEMBL2362981, mapped to UniProt Q13148. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | TAR DNA-binding protein 43 |
| Target Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
| UniProt | Q13148 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | TAR DNA-binding protein 43 |
| UniProt Accession | Q13148 |
| Component Type | Protein |
| Sequence Length | 414 aa |
TAR DNA-binding protein 43
Review this target as TAR DNA-binding protein 43, mapped to UniProt Q13148. Sequence length is 414 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL4635203 | 7.0 | IC50 | 100.0 | Preclinical |
| CHEMBL5653589 | 6.75 | Kd | 175.99 | Preclinical |
| CHEMBL3752910 | 6.09 | Kd | 813.51 | Preclinical |
| CHEMBL58 | 5.0 | IC50 | 10000.0 | Approved |
| CHEMBL134342 | 4.7 | IC50 | 19952.62 | Preclinical |
| CHEMBL1403899 | 4.7 | IC50 | 19952.62 | Preclinical |
| CHEMBL4638490 | 4.05 | Kd | 89000.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 4 | 0 | — |
| single protein format | 3 | 7 | 5.5 |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| assay format | 1 | 0 | — |