RL · CELL-LINE · Homo sapiens
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RL
Review this target as RL.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats RL as ChEMBL target CHEMBL2366175. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | RL |
| Target Type | CELL-LINE |
| Organism | Homo sapiens |
Reviewable protein naming and mapping context for this target snapshot.
Review this target as RL.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL67 | 8.85 | IC50 | 1.4 | Preclinical |
| CHEMBL428647 | 8.52 | IC50 | 3.0 | Approved |
| CHEMBL107 | 8.36 | IC50 | 4.4 | Approved |
| CHEMBL2205254 | 8.12 | IC50 | 7.6 | Preclinical |
| CHEMBL1090479 | 8.0 | EC50 | 10.0 | Preclinical |
| CHEMBL3747373 | 7.96 | IC50 | 11.0 | Preclinical |
| CHEMBL4780261 | 7.42 | IC50 | 38.0 | Preclinical |
| CHEMBL4785381 | 7.21 | IC50 | 61.0 | Preclinical |
| CHEMBL562903 | 7.16 | IC50 | 70.0 | Preclinical |
| CHEMBL325041 | 7.07 | IC50 | 86.09 | Clinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 41 | 161 | 5.5 |
| organism-based format | 4 | 0 | — |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 1 | 1 | 6.4 |