Acetylcholine receptor subunit beta-like 2 · SINGLE PROTEIN · Drosophila melanogaster
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As of 2026-09-14Protein identity stays anchored to UniProt P25162. Use UniProt P25162 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P25162 as the stable identity anchor, then attach disease evidence before program review.
Acetylcholine receptor subunit beta-like 2
Review this target as Acetylcholine receptor subunit beta-like 2, mapped to UniProt P25162. Sequence length is 519 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Acetylcholine receptor subunit beta-like 2 as ChEMBL target CHEMBL2366470, mapped to UniProt P25162. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Acetylcholine receptor subunit beta-like 2 |
| Target Type | SINGLE PROTEIN |
| Organism | Drosophila melanogaster |
| UniProt | P25162 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Acetylcholine receptor subunit beta-like 2 |
| UniProt Accession | P25162 |
| Component Type | Protein |
| Sequence Length | 519 aa |
Acetylcholine receptor subunit beta-like 2
Review this target as Acetylcholine receptor subunit beta-like 2, mapped to UniProt P25162. Sequence length is 519 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL1391421 | 9.92 | Ki | 0.12 | Preclinical |
| CHEMBL2270633 | 9.43 | IC50 | 0.37 | Preclinical |
| CHEMBL451432 | 8.92 | Ki | 1.2 | Preclinical |
| CHEMBL259727 | 8.66 | IC50 | 2.2 | Preclinical |
| CHEMBL406819 | 8.64 | IC50 | 2.3 | Preclinical |
| CHEMBL451432 | 8.57 | IC50 | 2.7 | Preclinical |
| CHEMBL406819 | 8.52 | Ki | 3.0 | Preclinical |
| CHEMBL148390 | 8.36 | IC50 | 4.4 | Preclinical |
| CHEMBL265941 | 8.14 | Ki | 7.2 | Preclinical |
| CHEMBL2251730 | 8.09 | IC50 | 8.2 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 5 | 9 | 7.2 |
| assay format | 4 | 19 | 7.6 |