Protoporphyrinogen IX oxidase · SINGLE PROTEIN · Cichorium intybus
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As of 2026-09-14Protein identity stays anchored to UniProt Q9SPL6. Use UniProt Q9SPL6 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt Q9SPL6 as the stable identity anchor, then attach disease evidence before program review.
Protoporphyrinogen oxidase
Review this target as Protoporphyrinogen IX oxidase, mapped to UniProt Q9SPL6. ChEMBL maps the protein component as Protoporphyrinogen oxidase. Sequence length is 555 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Protoporphyrinogen IX oxidase as ChEMBL target CHEMBL2366515, mapped to UniProt Q9SPL6. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Protoporphyrinogen IX oxidase |
| Target Type | SINGLE PROTEIN |
| Organism | Cichorium intybus |
| UniProt | Q9SPL6 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Protoporphyrinogen oxidase |
| UniProt Accession | Q9SPL6 |
| Component Type | Protein |
| Sequence Length | 555 aa |
Protoporphyrinogen oxidase
Review this target as Protoporphyrinogen IX oxidase, mapped to UniProt Q9SPL6. ChEMBL maps the protein component as Protoporphyrinogen oxidase. Sequence length is 555 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL278489 | 6.47 | IC50 | 338.84 | Preclinical |
| CHEMBL1888800 | 6.32 | IC50 | 478.63 | Preclinical |
| CHEMBL1605837 | 6.07 | IC50 | 851.14 | Preclinical |
| CHEMBL2287129 | 5.35 | IC50 | 4466.84 | Preclinical |
| CHEMBL2287127 | 4.73 | IC50 | 18620.87 | Preclinical |
| CHEMBL2287128 | 4.62 | IC50 | 23988.33 | Preclinical |
| CHEMBL2287126 | 4.02 | IC50 | 95499.26 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 2 | 7 | 5.4 |