B2 bradykinin receptor · SINGLE PROTEIN · Rattus norvegicus
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As of 2026-09-14Protein identity stays anchored to UniProt P25023. Use UniProt P25023 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P25023 as the stable identity anchor, then attach disease evidence before program review.
B2 bradykinin receptor
Review this target as B2 bradykinin receptor, mapped to UniProt P25023. Sequence length is 396 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats B2 bradykinin receptor as ChEMBL target CHEMBL2501, mapped to UniProt P25023. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | B2 bradykinin receptor |
| Target Type | SINGLE PROTEIN |
| Organism | Rattus norvegicus |
| UniProt | P25023 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | B2 bradykinin receptor |
| UniProt Accession | P25023 |
| Component Type | Protein |
| Sequence Length | 396 aa |
B2 bradykinin receptor
Review this target as B2 bradykinin receptor, mapped to UniProt P25023. Sequence length is 396 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL1907651 | 10.64 | Ki | 0.023 | Preclinical |
| CHEMBL2028850 | 10.11 | Ki | 0.077 | Approved |
| CHEMBL1907652 | 9.51 | Ki | 0.31 | Preclinical |
| CHEMBL2028850 | 9.5 | Kd | 0.3162 | Approved |
| CHEMBL406291 | 9.34 | Ki | 0.46 | Clinical |
| CHEMBL3038099 | 9.31 | Kd | 0.4898 | Preclinical |
| CHEMBL2112937 | 9.3 | Ki | 0.5 | Preclinical |
| CHEMBL308468 | 9.3 | Ki | 0.5 | Preclinical |
| CHEMBL2112044 | 9.22 | Ki | 0.6 | Preclinical |
| CHEMBL431562 | 9.22 | Ki | 0.6 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell membrane format | 3 | 23 | 7.6 |
| cell-based format | 2 | 3 | 9.2 |
| tissue-based format | 2 | 0 | — |
| assay format | 1 | 1 | 6.4 |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| tissue-based format | 3 | 17 | 8.0 |
| cell-based format | 1 | 2 | 6.9 |