Type-1 angiotensin II receptor B · SINGLE PROTEIN · Rattus norvegicus
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As of 2026-09-13Protein identity stays anchored to UniProt P29089. Use UniProt P29089 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P29089 as the stable identity anchor, then attach disease evidence before program review.
Type-1 angiotensin II receptor B
Review this target as Type-1 angiotensin II receptor B, mapped to UniProt P29089. Sequence length is 359 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Type-1 angiotensin II receptor B as ChEMBL target CHEMBL263, mapped to UniProt P29089. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Type-1 angiotensin II receptor B |
| Target Type | SINGLE PROTEIN |
| Organism | Rattus norvegicus |
| UniProt | P29089 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Type-1 angiotensin II receptor B |
| UniProt Accession | P29089 |
| Component Type | Protein |
| Sequence Length | 359 aa |
Type-1 angiotensin II receptor B
Review this target as Type-1 angiotensin II receptor B, mapped to UniProt P29089. Sequence length is 359 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL317343 | 9.8 | IC50 | 0.16 | Preclinical |
| CHEMBL216061 | 9.8 | Ki | 0.16 | Preclinical |
| CHEMBL411997 | 9.64 | Ki | 0.23 | Preclinical |
| CHEMBL279629 | 9.51 | IC50 | 0.31 | Preclinical |
| CHEMBL408403 | 9.51 | Ki | 0.31 | Approved |
| CHEMBL7550 | 9.4 | IC50 | 0.4 | Preclinical |
| CHEMBL408403 | 9.4 | IC50 | 0.4 | Approved |
| CHEMBL34866 | 9.36 | IC50 | 0.44 | Preclinical |
| CHEMBL284918 | 9.36 | IC50 | 0.44 | Preclinical |
| CHEMBL35381 | 9.21 | Ki | 0.6194 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| assay format | 17 | 121 | 7.0 |
| cell membrane format | 10 | 202 | 7.2 |
| single protein format | 10 | 115 | 7.5 |
| tissue-based format | 3 | 13 | 8.4 |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| organism-based format | 2 | 0 | — |
| tissue-based format | 2 | 2 | 7.6 |
| cell membrane format | 1 | 2 | 7.5 |