Vasopressin V1b receptor · SINGLE PROTEIN · Rattus norvegicus
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Structured disease, protein, and project context should read before the lower-level identity rail.
As of 2026-09-13Protein identity stays anchored to UniProt P48974. Use UniProt P48974 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P48974 as the stable identity anchor, then attach disease evidence before program review.
Vasopressin V1b receptor
Review this target as Vasopressin V1b receptor, mapped to UniProt P48974. Sequence length is 425 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Vasopressin V1b receptor as ChEMBL target CHEMBL2659, mapped to UniProt P48974. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Vasopressin V1b receptor |
| Target Type | SINGLE PROTEIN |
| Organism | Rattus norvegicus |
| UniProt | P48974 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Vasopressin V1b receptor |
| UniProt Accession | P48974 |
| Component Type | Protein |
| Sequence Length | 425 aa |
Vasopressin V1b receptor
Review this target as Vasopressin V1b receptor, mapped to UniProt P48974. Sequence length is 425 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL265859 | 10.4 | Ki | 0.04 | Preclinical |
| CHEMBL375324 | 9.89 | Ki | 0.13 | Preclinical |
| CHEMBL412972 | 9.8 | Ki | 0.16 | Preclinical |
| CHEMBL385739 | 9.72 | Ki | 0.19 | Preclinical |
| CHEMBL1429 | 9.7 | Ki | 0.2 | Approved |
| CHEMBL221436 | 9.6 | Ki | 0.25 | Preclinical |
| CHEMBL412973 | 9.6 | Ki | 0.25 | Preclinical |
| CHEMBL375188 | 9.59 | Ki | 0.26 | Preclinical |
| CHEMBL373742 | 9.54 | Ki | 0.29 | Approved |
| CHEMBL373968 | 9.42 | Ki | 0.38 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 4 | 48 | 7.9 |
| single protein format | 3 | 2 | 6.1 |
| cell membrane format | 1 | 0 | — |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 2 | 0 | — |