rRNA adenine N-6-methyltransferase · SINGLE PROTEIN · Streptococcus pneumoniae
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As of 2026-09-14Protein identity stays anchored to UniProt P21236. Use UniProt P21236 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P21236 as the stable identity anchor, then attach disease evidence before program review.
rRNA adenine N-6-methyltransferase
Review this target as rRNA adenine N-6-methyltransferase, mapped to UniProt P21236. Sequence length is 245 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats rRNA adenine N-6-methyltransferase as ChEMBL target CHEMBL2757, mapped to UniProt P21236. Disease framing currently uses the Open Targets-ready proxy contract.
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Start here when your first question is whether rRNA adenine N-6-methyltransferase is the right protein anchor across sources, using UniProt P21236 as the stable mapping.
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| Preferred Name | rRNA adenine N-6-methyltransferase |
| Target Type | SINGLE PROTEIN |
| Organism | Streptococcus pneumoniae |
| UniProt | P21236 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | rRNA adenine N-6-methyltransferase |
| UniProt Accession | P21236 |
| Component Type | Protein |
| Sequence Length | 245 aa |
rRNA adenine N-6-methyltransferase
Review this target as rRNA adenine N-6-methyltransferase, mapped to UniProt P21236. Sequence length is 245 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL340522 | 5.7 | Ki | 2000.0 | Preclinical |
| CHEMBL125249 | 5.52 | Ki | 3000.0 | Preclinical |
| CHEMBL127777 | 5.4 | Ki | 4000.0 | Preclinical |
| CHEMBL124572 | 5.22 | Ki | 6000.0 | Preclinical |
| CHEMBL125085 | 5.12 | Ki | 7500.0 | Preclinical |
| CHEMBL331440 | 5.1 | Ki | 8000.0 | Preclinical |
| CHEMBL333812 | 5.05 | Ki | 9000.0 | Preclinical |
| CHEMBL126068 | 5.0 | Ki | 10000.0 | Preclinical |
| CHEMBL338033 | 5.0 | Ki | 10000.0 | Preclinical |
| CHEMBL330769 | 4.9 | Ki | 12500.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 2 | 16 | 4.8 |