Adenylate cyclase type 5 · SINGLE PROTEIN · Rattus norvegicus
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As of 2026-09-13Protein identity stays anchored to UniProt Q04400. Use UniProt Q04400 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt Q04400 as the stable identity anchor, then attach disease evidence before program review.
Adenylate cyclase type 5
Review this target as Adenylate cyclase type 5, mapped to UniProt Q04400. Sequence length is 1262 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Adenylate cyclase type 5 as ChEMBL target CHEMBL2880, mapped to UniProt Q04400. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Adenylate cyclase type 5 |
| Target Type | SINGLE PROTEIN |
| Organism | Rattus norvegicus |
| UniProt | Q04400 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Adenylate cyclase type 5 |
| UniProt Accession | Q04400 |
| Component Type | Protein |
| Sequence Length | 1262 aa |
Adenylate cyclase type 5
Review this target as Adenylate cyclase type 5, mapped to UniProt Q04400. Sequence length is 1262 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL25856 | 8.67 | EC50 | 2.15 | Clinical |
| CHEMBL320428 | 8.0 | EC50 | 10.0 | Preclinical |
| CHEMBL318338 | 8.0 | EC50 | 10.0 | Preclinical |
| CHEMBL319707 | 6.94 | EC50 | 114.0 | Preclinical |
| CHEMBL106801 | 6.89 | EC50 | 130.0 | Preclinical |
| CHEMBL104772 | 6.87 | EC50 | 134.0 | Preclinical |
| CHEMBL106836 | 6.83 | EC50 | 148.0 | Preclinical |
| CHEMBL106116 | 6.82 | EC50 | 151.0 | Preclinical |
| CHEMBL13078 | 6.56 | EC50 | 275.0 | Preclinical |
| CHEMBL104141 | 6.48 | EC50 | 333.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| assay format | 14 | 10 | 7.0 |
| cell-based format | 12 | 0 | — |
| single protein format | 3 | 1 | 7.6 |
| cell membrane format | 1 | 4 | 6.1 |
| tissue-based format | 1 | 6 | 5.2 |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-free format | 2 | 0 | — |
| cell membrane format | 1 | 1 | 7.3 |
| cell-based format | 1 | 0 | — |
| tissue-based format | 1 | 0 | — |