Compound Detail
CHEMBL320428
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Basic Information
| ChEMBL ID | CHEMBL320428 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | RMDMGQSKVJJQEX-NFBKMPQASA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
4
Publications
0
Known Names
Molecular Properties
343.4
MW (Da)
4.31
ALogP
3
HBA
3
HBD
52.5
PSA (Ų)
0.58
QED
0
Ro5 Violations
1
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
EC50 1 meas. best 8.0
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Adenylate cyclase type 5 CHEMBL2880 | EC50 | 8.0 | 8.0 | 10.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Adenylate cyclase type 5 | EC50 | = | 10.0 | nM | 8.0 | Effective concentration as Adenylate cyclase activity was measured in rat homoge... | 7636869 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 7636869 | 10.1021/jm00016a009 | Adenylate cyclase type 5 | 2 |
| 7636869 | 10.1021/jm00016a009 | D(1A) dopamine receptor | 1 |
| 7636869 | 10.1021/jm00016a009 | D(2) dopamine receptor | 1 |
| 7636869 | 10.1021/jm00016a009 | Dopamine receptors; D1 & D2 | 1 |
Data from ChEMBL 36 via Core Engine